Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493591 | 0.93 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL493677 | 0.87 | KMT2A (0.49) | KDM4EKMT2AMAPTHPGD | |
| SCHEMBL493674 | 0.87 | TDP1 (0.38) | KDM4EKMT2ATDP1SMN1; SMN2HTT | |
| SCHEMBL493647 | 0.86 | KDM4E (0.48) | KDM4EGAAKMT2ASMN1; SMN2HTT | |
| SCHEMBL493354 | 0.86 | CCR2 (0.42) | KDM4EKMT2ATDP1SMN1; SMN2HTT | |
| SCHEMBL493800 | 0.85 | GHSR (0.38) | KDM4EKMT2ATDP1SMN1; SMN2HTT | |
| SCHEMBL493060 | 0.85 | FAAH (0.44) | SMN1; SMN2HTTTSHRNPC1 | |
| SCHEMBL493502 | 0.84 | KMT2A (0.40) | GAAKMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL493221 | 0.84 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2HTTTSHRMAPT | |
| SCHEMBL493049 | 0.82 | KMT2A (0.38) | KDM4EKMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |