Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493677 | 0.90 | KMT2A (0.49) | KMT2AHPGDMAPT | |
| SCHEMBL493274 | 0.88 | LIPG (0.36) | TSHRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL493800 | 0.86 | GHSR (0.38) | KMT2ATSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL494415 | 0.86 | TSHR (0.42) | KMT2AALDH1A1MEN1TSHRNPC1 | |
| SCHEMBL493049 | 0.86 | KMT2A (0.38) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL493060 | 0.85 | FAAH (0.44) | TSHRNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL493591 | 0.85 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2LMNAMAPTPKM | |
| SCHEMBL493674 | 0.85 | TDP1 (0.38) | KMT2AALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL493221 | 0.85 | SMN1; SMN2 (0.56) | KMT2AALDH1A1MEN1TSHRNPC1 | |
| SCHEMBL492980 | 0.84 | KDM4E (0.45) | KMT2AALDH1A1TSHRNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |