Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494598 | 0.93 | LMNA (0.44) | MAPTLMNATAS1R3TAS1R1TSHR | |
| SCHEMBL493677 | 0.88 | KMT2A (0.49) | MAPTKDM4EKMT2A | |
| SCHEMBL493674 | 0.87 | TDP1 (0.38) | CCR2MAPTTSHRTDP1HTT | |
| SCHEMBL492980 | 0.86 | KDM4E (0.45) | MAPTLMNATSHRTDP1HTT | |
| SCHEMBL493591 | 0.85 | SMN1; SMN2 (0.47) | CCR2KCNH2MAPTLMNASMN1; SMN2 | |
| SCHEMBL493800 | 0.84 | GHSR (0.38) | CCR2MAPTTSHRTDP1HTT | |
| SCHEMBL493060 | 0.83 | FAAH (0.44) | CCR2KCNH2TSHRHTTSMN1; SMN2 | |
| SCHEMBL493502 | 0.82 | KMT2A (0.40) | CCR2MAPTLMNATSHRSMN1; SMN2 | |
| SCHEMBL493221 | 0.82 | SMN1; SMN2 (0.56) | MAPTLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL493049 | 0.82 | KMT2A (0.38) | CCR2MAPTSMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |