Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492980 | 0.93 | KDM4E (0.45) | SMN1; SMN2MAPTLMNAPKMKMT2A | |
| SCHEMBL493677 | 0.87 | KMT2A (0.49) | MAPTKMT2A | |
| SCHEMBL493674 | 0.87 | TDP1 (0.38) | SMN1; SMN2MAPTKMT2ACCR2 | |
| SCHEMBL493863 | 0.86 | LMNA (0.48) | SMN1; SMN2MAPTLMNAPKMKMT2A | |
| SCHEMBL493354 | 0.85 | CCR2 (0.42) | SMN1; SMN2MAPTLMNAPKMKMT2A | |
| SCHEMBL493502 | 0.85 | KMT2A (0.40) | SMN1; SMN2MAPTLMNAPKMKMT2A | |
| SCHEMBL493221 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTLMNAPKMKMT2A | |
| SCHEMBL493800 | 0.85 | GHSR (0.38) | SMN1; SMN2MAPTKMT2ACCR2 | |
| SCHEMBL493060 | 0.84 | FAAH (0.44) | SMN1; SMN2CCR2KCNH2 | |
| SCHEMBL493274 | 0.83 | LIPG (0.36) | SMN1; SMN2LMNACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |