Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494117 | 0.93 | HPGD (0.50) | KMT2AHPGD | |
| SCHEMBL493502 | 0.90 | KMT2A (0.40) | KMT2AMAPTHPGD | |
| SCHEMBL493354 | 0.88 | CCR2 (0.42) | KMT2AKDM4EMAPT | |
| SCHEMBL493674 | 0.88 | TDP1 (0.38) | KMT2AKDM4EMAPTHPGD | |
| SCHEMBL492980 | 0.87 | KDM4E (0.45) | KMT2AKDM4EMAPTHPGD | |
| SCHEMBL493591 | 0.87 | SMN1; SMN2 (0.47) | KMT2AMAPT | |
| SCHEMBL493737 | 0.86 | KMT2A (0.49) | KMT2AKDM4EMAPTHPGD | |
| SCHEMBL493800 | 0.85 | GHSR (0.38) | KMT2AKDM4EMAPT | |
| SCHEMBL493060 | 0.84 | FAAH (0.44) | — | |
| SCHEMBL493221 | 0.84 | SMN1; SMN2 (0.56) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |