Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493502 | 0.88 | KMT2A (0.40) | RAB9ACCR2HPGDNPC1SMN1; SMN2 | |
| SCHEMBL492929 | 0.87 | RAB9A (0.37) | LIPGACKR3RAB9ACCR2HPGD | |
| SCHEMBL493049 | 0.85 | KMT2A (0.38) | RAB9ACCR2NPC1SMN1; SMN2SMYD3 | |
| SCHEMBL493674 | 0.84 | TDP1 (0.38) | RAB9ACCR2HPGDNPC1SMN1; SMN2 | |
| SCHEMBL493800 | 0.84 | GHSR (0.38) | RAB9ACCR2NPC1SMN1; SMN2TSHR | |
| SCHEMBL493060 | 0.83 | FAAH (0.44) | LIPGRAB9ACCR2NPC1SMN1; SMN2 | |
| SCHEMBL493591 | 0.83 | SMN1; SMN2 (0.47) | CCR2SMN1; SMN2LMNA | |
| SCHEMBL493677 | 0.83 | KMT2A (0.49) | HPGD | |
| SCHEMBL493221 | 0.82 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2TSHRLMNA | |
| SCHEMBL492980 | 0.82 | KDM4E (0.45) | HPGDNPC1SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |