Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 1.00 |
| ▸ | GLA | P06280 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | SNCA | P37840 | 1/20 | 0.66 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.64 |
| ▸ | FLT4 | P35916 | 2/20 | 0.64 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29523038 | 1.00 | APP (1.00) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL2628266 | 1.00 | APP (1.00) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL13853330 | 0.93 | APP (1.00) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL8397393 | 0.86 | APP (0.76) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL24155562 | 0.86 | APP (0.76) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL29474819 | 0.86 | RAB9A (0.81) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL366824 | 0.86 | RAB9A (0.81) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL24295138 | 0.84 | RAB9A (0.79) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL14195557 | 0.83 | APP (0.71) | APPGLAGAAMEN1KMT2A | |
| SCHEMBL12472555 | 0.83 | APP (0.71) | APPGLAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025224727-A1 | p53 amyloid-binding composition, method, and kit thereof | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2025-10-30 | — | — | WO | claimed |
| CN-120008222-A | Overheat protection system is prevented in solar thermal-arrest field | 西藏隆晟能源管理有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-116693933-A | Method for degrading plastics | 北京化工大学 | 2023-09-05 | — | — | CN | claimed |
| EP-2802871-B1 | CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER | TAKEDA PHARMACEUTICALS CO (JP) | 2022-07-27 | — | — | EP | claimed |
| EP-2435844-A1 | SYSTEMS, DEVICES, METHODS, AND COMPOSITIONS INCLUDING FERROMAGNETIC STRUCTURES | Searete LLC (US) | 2012-04-04 | — | — | EP | claimed |
| US-20100303731-A1 | Systems, devices, methods, and compositions including selectively accessible ferromagnetic structures | SEARETE LLC | 2010-12-02 | — | — | US | claimed |
| WO-2010138202-A1 | SYSTEMS, DEVICES, METHODS, AND COMPOSITIONS INCLUDING FERROMAGNETIC STRUCTURES | SEARETE, LLC (US) | 2010-12-02 | — | — | WO | claimed |
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | The Government of the United States of America as represented (US) | 2008-04-10 | — | — | US | claimed |
| EP-3129065-B1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | AKAMARA THERAPEUTICS INC (US) | 2026-05-13 | — | — | EP | disclosed |
| CN-122010854-A | Compound for preparing photoresist film, photosensitive resin composition and photosensitive laminate | 珦盛新材料(珠海)有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4724816-A2 | METHODS FOR DETECTING THE PRESENCE OF AT LEAST ONE MISFOLDED FORM OF SOD1 IN A BIOLOGICAL SAMPLE | Mclaughlin Research Institute for Biomedical Sciences (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260022227-A1 | METHOD FOR DEGRADING AND DECOMPOSING PLASTIC USING ENZYMES EXPRESSED BY LEPIDOPTERA | THE AMERICAN UNIVERSITY IN CAIRO (EG) | 2026-01-22 | — | — | US | disclosed |
| US-12493244-B2 | Photosensitive resin composition, photosensitive dry film, and pattern formation method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-12-09 | — | — | US | disclosed |
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-11-06 | — | — | US | disclosed |
| CN-1535268-A | Thioflavin derivatives for antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid deposits | ƥ�ȱ���ѧ | 2004-10-06 | — | — | CN | disclosed |
| WO-2004083195-A1 | BENZOTHIAZOLE DERIVATIVE COMPOUNDS, COMPOSITIONS AND USES | UNIVERSITY OF PITTSBURGH (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20030236391-A1 | Imaging amyloid deposits in living patients, with an amyloid binding agents having radiolabeled iodine; radiotherapy | UNIVERSITY OF PITTSBURGH | 2003-12-25 | — | — | US | disclosed |
| EP-1334091-A2 | THIOFLAVIN DERIVATIVES AND THEIR USE IN DIAGNOSIS AND THERAPY OF ALZHEIMER'S DISEASE | UNIVERSITY OF PITTSBURGH (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20020133019-A1 | Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and vivo imaging and prevention of amyloid deposition | PITTSBURGH, UNIVERSITY OF | 2002-09-19 | — | — | US | disclosed |
| WO-2002016333-A2 | THIOFLAVIN DERIVATIVES AND THEIR USE IN DIAGNOSIS AND THERAPHY OF ALZHEIMER'S DISEASE | UNIVERSITY OF PITTSBURGH (US) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | HSPBP1, HSPA2, HSPA8 | APP 36/4885GLA 1510/4885GAA 1890/4885 |
| US-20260022227-A1 | METHOD FOR DEGRADING AND DECOMPOSING PLASTIC USING ENZYMES EXPRESSED BY LEPIDOPTERA | CMBL, LCT, LIPE | APP 2917/4885GLA 1071/4885GAA 235/4885 |
| US-20020133019-A1 | Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and vivo imaging and prevention of amyloid deposition | APP, PSEN2, MAPT | APP 1/4885GLA 148/4885GAA 1121/4885 |
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | APP 21/4885GLA 1727/4885GAA 4005/4885 |
| US-20030236391-A1 | Imaging amyloid deposits in living patients, with an amyloid binding agents having radiolabeled iodine; radiotherapy | TTR, APP, BACE1 | APP 2/4885GLA 133/4885GAA 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.