Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493677 | 0.93 | KMT2A (0.49) | HPGDKMT2A | |
| SCHEMBL494598 | 0.89 | LMNA (0.44) | HPGDKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL493429 | 0.87 | HPGD (0.51) | HPGDKMT2A | |
| SCHEMBL493063 | 0.84 | SMN1; SMN2 (0.59) | KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL493654 | 0.84 | KMT2A (0.41) | KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL493502 | 0.82 | KMT2A (0.40) | HPGDKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL493354 | 0.81 | CCR2 (0.42) | KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL493674 | 0.81 | TDP1 (0.38) | HPGDKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL492980 | 0.80 | KDM4E (0.45) | HPGDKMT2ACYP1A2CYP2C9TSHR | |
| SCHEMBL493591 | 0.80 | SMN1; SMN2 (0.47) | KMT2ACYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |