Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492882 | 0.82 | ALDH1A1 (0.40) | ACLYSLC9A3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL493606 | 0.72 | ACLY (0.38) | ACLYKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL493566 | 0.71 | BDKRB1 (0.42) | KDM4EALDH1A1L3MBTL1TDP1GSTO1 | |
| SCHEMBL3998000 | 0.69 | ALDH1A1 (0.44) | ACLYKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL642948 | 0.68 | GAA (0.48) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL645268 | 0.68 | MAPT (0.45) | ACLYKDM4EL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL3993365 | 0.67 | GSTO1 (0.42) | ACLYKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL644589 | 0.67 | GAA (0.47) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5130046 | 0.65 | KDM4E (0.46) | KDM4ETDP1 | |
| SCHEMBL11576786 | 0.63 | FABP4 (0.47) | ALDH1A1L3MBTL1PKMNPSR1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | ACLY 80/4885SLC9A3 2717/4885KDM4E 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.