Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493049 | 0.93 | KMT2A (0.38) | KMT2ARAB9ANCOA1NCOA3POLB | |
| SCHEMBL493213 | 0.87 | KMT2A (0.41) | KMT2ARAB9ANCOA1NCOA3POLB | |
| SCHEMBL494117 | 0.84 | HPGD (0.50) | KMT2ASMN1; SMN2TSHR | |
| SCHEMBL493063 | 0.83 | SMN1; SMN2 (0.59) | KMT2ARAB9APOLBNPC1SMN1; SMN2 | |
| SCHEMBL494598 | 0.82 | LMNA (0.44) | KMT2ARAB9ANPC1SMN1; SMN2SMYD3 | |
| SCHEMBL493674 | 0.82 | TDP1 (0.38) | KMT2ARAB9ACCR2NPC1SMN1; SMN2 | |
| SCHEMBL493800 | 0.82 | GHSR (0.38) | KMT2ARAB9ANCOA1NCOA3POLB | |
| SCHEMBL493502 | 0.79 | KMT2A (0.40) | KMT2ARAB9ACCR2NPC1SMN1; SMN2 | |
| SCHEMBL493274 | 0.78 | LIPG (0.36) | RAB9ACCR2NPC1SMN1; SMN2SMYD3 | |
| SCHEMBL493060 | 0.77 | FAAH (0.44) | RAB9ACCR2NPC1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |