Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908662 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| SCHEMBL13387500 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL31601633 | 0.98 | L3MBTL1 (0.43) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| SCHEMBL24102991 | 0.94 | L3MBTL1 (0.41) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| SCHEMBL29028068 | 0.94 | L3MBTL1 (0.41) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| SCHEMBL29028066 | 0.94 | L3MBTL1 (0.41) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| SCHEMBL8281978 | 0.92 | L3MBTL1 (0.42) | L3MBTL1ALOX15METAP2GAAALDH1A1 | |
| SCHEMBL21107395 | 0.90 | ALDH1A1 (0.48) | L3MBTL1METAP2ALDH1A1NPSR1TSHR | |
| SCHEMBL1320791 | 0.90 | ALDH1A1 (0.48) | L3MBTL1METAP2ALDH1A1NPSR1TSHR | |
| Hydrochloric Acid SCHEMBL5967498 | 0.88 | ALDH1A1 (0.47) | L3MBTL1METAP2ALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150989-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2023-05-18 | — | — | US | disclosed |
| US-10781218-B2 | Substituted inhibitors of menin-MLL and methods of use | KURA ONCOLOGY, INC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20190092784-A1 | SUBSTITUTED INHIBITORS OF MENIN-MLL AND METHODS OF USE | KURA ONCOLOGY, INC. | 2019-03-28 | — | — | US | disclosed |
| EP-2598486-B1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS | NOVARTIS AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| CN-103339111-A | Bicyclic acetyl-CoA carboxylase inhibitors | NOVARTIS AG | 2013-10-02 | — | — | CN | disclosed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| EP-2173735-B1 | IMIDAZOLE DERIVATIVES AS CCR2 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2012-01-11 | — | — | EP | disclosed |
| US-7935707-B2 | Imidazole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-05-03 | — | — | US | disclosed |
| EP-2173735-A1 | IMIDAZOLE DERIVATIVES AS CCR2 RECEPTOR ANTAGONISTS | F. Hoffmann-Roche AG (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-20090012063-A1 | Novel imidazole derivatives | HOFFMANN-LA ROCHE, INC. | 2009-01-08 | — | — | US | disclosed |
| WO-2009003861-A1 | IMIDAZOLE DERIVATIVES AS CCR2 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-01-08 | — | — | WO | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20060148649-A1 | Substituted n-aryl nitrogen heterocycles | BAYER CROPSCIENCE GMBH PATENTS AND LICENSING (DE) | 2006-07-06 | — | — | US | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092784-A1 | SUBSTITUTED INHIBITORS OF MENIN-MLL AND METHODS OF USE | MLLT1, MEN1, MLLT3 | L3MBTL1 263/4885ALOX15 4452/4885METAP2 655/4885 |
| US-20230150989-A1 | HERBICIDAL MALONAMIDES | DDT, DHRS9, CA9 | L3MBTL1 1134/4885ALOX15 3014/4885METAP2 1797/4885 |
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | L3MBTL1 4753/4885ALOX15 585/4885METAP2 3381/4885 |
| US-20090012063-A1 | Novel imidazole derivatives | CCR2, CCR1, CCR3 | L3MBTL1 3575/4885ALOX15 4426/4885METAP2 1521/4885 |
| US-10781218-B2 | Substituted inhibitors of menin-MLL and methods of use | MLLT1, MEN1, MLLT3 | L3MBTL1 376/4885ALOX15 3988/4885METAP2 1055/4885 |
| US-20060148649-A1 | Substituted n-aryl nitrogen heterocycles | NAT1, CBR3, NPM1 | L3MBTL1 2095/4885ALOX15 3991/4885METAP2 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.