Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097155 | 0.96 | LMNA (0.51) | MAOAMAOBEPHX1KDM4ELMNA | |
| SCHEMBL7096381 | 0.94 | EPHX1 (0.50) | MAOAMAOBEPHX1KDM4ELMNA | |
| SCHEMBL5682291 | 0.91 | MAOA (0.50) | MAOAMAOBEPHX1KDM4ELMNA | |
| SCHEMBL8549833 | 0.88 | EPHX1 (0.60) | EPHX1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL8550840 | 0.87 | ALDH1A1 (0.60) | EPHX1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL8550250 | 0.87 | EPHX2 (0.50) | EPHX1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL8549863 | 0.83 | GHSR (0.49) | EPHX1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL15914264 | 0.83 | CNR1 (0.53) | EPHX1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL8549984 | 0.83 | EPHX1 (0.43) | EPHX1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL7098401 | 0.83 | MARS1 (0.55) | EPHX1KDM4ELMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227023-A1 | Radiating; ink receptive layer has second phenolic resin polymeric binder different from first ; soluble in developer; free of dissolution inhibitors; first binder has comonomers of (meth)acrylamide,N-substituted cyclic imide, 2-[3-(4-hydroxyphenyl)ureido]ethyl methacrylate, and/or acrylonitrile | KODAK POLYCHROME GRAPHICS, GMBH (DE) | 2008-09-18 | — | — | US | claimed |
| US-9822206-B2 | Copolymers for near-infrared radiation-sensitive coating compositions for positive-working thermal lithographic printing plates | MYLAN GROUP (VN) | 2017-11-21 | — | — | US | disclosed |
| EP-2566900-B1 | COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES | MYLAN GROUP (VN) | 2016-02-17 | — | — | EP | disclosed |
| US-20140221591-A1 | COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES | MYLAN GROUP (VN) | 2014-08-07 | — | — | US | disclosed |
| US-20080227023-A1 | Radiating; ink receptive layer has second phenolic resin polymeric binder different from first ; soluble in developer; free of dissolution inhibitors; first binder has comonomers of (meth)acrylamide,N-substituted cyclic imide, 2-[3-(4-hydroxyphenyl)ureido]ethyl methacrylate, and/or acrylonitrile | KODAK POLYCHROME GRAPHICS, GMBH (DE) | 2008-09-18 | — | — | US | disclosed |
| EP-1368413-A4 | TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS | KODAK POLYCHROME GRAPHICS LLC (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1147884-B1 | Planographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-6902860-B2 | Polyurethanes | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-06-07 | — | — | US | disclosed |
| US-6749984-B2 | POSITIVE-TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR THAT CAN BE WRITTEN BY HEAT FROM AN INFRARED LASER, A THERMAL HEAD OR THE LIKE, AND USED FOR SO-CALLED DIRECT PLATE-MAKING | FUJI PHOTO FILM CO., LTD. (JP) | 2004-06-15 | — | — | US | disclosed |
| US-20040023155-A1 | Polymeric molecules that comprises a quadruple hydrogen bonding unit, particularly from 6-methylisocytosine reacted with a diisocyanate; acrylic, phenolic, polyester and/or polyurethane units | KODAK POLYCHROME GRAPHICS, LLC | 2004-02-05 | — | — | US | disclosed |
| EP-1368413-A1 | TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS | Kodak Polychrome Graphics (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-0737896-B1 | Photosensitive composition and photosensitive planographic printing plate | KODAK POLYCHROME GRAPHICS JP (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-20020160299-A1 | Polyurethanes | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2002-10-31 | — | — | US | disclosed |
| WO-2002053627-A1 | TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2002-07-11 | — | — | WO | disclosed |
| US-20010039895-A1 | POSITIVE-TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR THAT CAN BE WRITTEN BY HEAT FROM AN INFRARED LASER, A THERMAL HEAD OR THE LIKE, AND USED FOR SO-CALLED DIRECT PLATE-MAKING | FUJIFILM CORPORATION (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-1147884-A2 | Planographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5731127-A | WEAR RESISTANCE, SOLVENT RESISTANCE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0737896-A2 | Photosensitive composition and photosensitive planographic printing plate | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1996-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160299-A1 | Polyurethanes | PUF60, PCBP1, PARG | MAOA 2612/4885MAOB 3696/4885EPHX1 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.