SCHEMBL4948200

SCHEMBL4948200

COc1ccc(C(NC[C@H]2O[C@@H](n3cc(C)c(=O)[nH]c3=O)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.62
TK1 P04183 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561711 1.00 DUT (0.62) DUTTK1
SCHEMBL2561714 1.00 DUT (0.62) DUTTK1
SCHEMBL13589375 1.00 DUT (0.62) DUTTK1
SCHEMBL152180 0.96 DUT (0.58) DUT
Phosphoramidic Acid SCHEMBL6514620 0.95 DUT (0.57) DUT
SCHEMBL8655889 0.93 DUT (0.71) DUT
SCHEMBL8655891 0.93 DUT (0.71) DUT
SCHEMBL3923808 0.93 DUT (0.59) DUT
SCHEMBL22819137 0.90 DUT (0.49) DUTTK1
SCHEMBL8438743 0.87 TK1 (0.54) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442788-B2 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-10-28 US disclosed
US-6872809-B2 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2005-03-29 US disclosed
US-20030208050-A1 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-11-06 US disclosed
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-08-28 US disclosed
EP-1295892-A1 ANTISENSE MOLECULES AND METHOD OF CONTROLLING EXPRESSION OF GENE FUNCTION BY USING THE SAME Japan Science and Technology Corporation (JP) 2003-03-26 EP disclosed
EP-1295891-A1 NUCLEOSIDE DERIVATIVES Japan Science and Technology Corporation (JP) 2003-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same RNGTT, RNMT, UPF1 DUT 81/4885TK1 173/4885
US-20030208050-A1 Nucleoside derivatives RIMKLA, MTHFD1, AADAT DUT 100/4885TK1 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.