Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | ILK | Q13418 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103181 | 0.86 | ALDH1A1 (0.43) | MAPK10MAPK8MAPK9ILKKDM4E | |
| SCHEMBL5096401 | 0.86 | ILK (0.48) | MAPK10MAPK8MAPK9ILKKDM4E | |
| SCHEMBL5596244 | 0.86 | CDK1 (0.43) | MAPK10MAPK8MAPK9ILKKDM4E | |
| SCHEMBL5100115 | 0.85 | PTGS1 (0.41) | MAPK10MAPK8MAPK9ILKNPC1 | |
| SCHEMBL5138885 | 0.85 | CSNK1D (0.41) | MAPK10MAPK8MAPK9ILKKDM4E | |
| SCHEMBL5103578 | 0.84 | SMN1; SMN2 (0.46) | KDM4EALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL5110395 | 0.84 | ALDH1A1 (0.46) | MAPK10MAPK8MAPK9MKNK1MKNK2 | |
| SCHEMBL5596497 | 0.83 | KDM4E (0.42) | MAPK10MAPK9ILKKDM4EALDH1A1 | |
| SCHEMBL4949154 | 0.82 | MKNK1 (0.47) | MAPK10MAPK8MAPK9MKNK1MKNK2 | |
| SCHEMBL5596747 | 0.79 | CDK1 (0.35) | MAPK10MAPK8MAPK9ILKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122825-A1 | EFFICIENT FUNCTIONAL GENOMICS PLATFORM | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-05-05 | — | — | US | disclosed |