Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 6/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ASPH | Q12797 | 3/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577580 | 0.83 | KDM5B (0.46) | LMNASMN1; SMN2KDM5AKDM4CKDM4E | |
| SCHEMBL19305015 | 0.82 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2KDM5AKDM4CKDM4E | |
| SCHEMBL15351593 | 0.81 | ATR (0.51) | LMNASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL19857473 | 0.80 | KDM4E (0.55) | KDM5AKDM4CKDM4EASPHKDM8 | |
| SCHEMBL15527710 | 0.80 | GABRP (0.46) | LMNAKDM5AKDM4CKDM4EASPH | |
| SCHEMBL14836840 | 0.79 | GABRP (0.39) | LMNASMN1; SMN2KDM5AKDM4CKDM4E | |
| SCHEMBL28260878 | 0.79 | KDM4E (0.39) | LMNASMN1; SMN2KDM5AKDM4CKDM4E | |
| SCHEMBL6931488 | 0.79 | NOS2 (0.55) | LMNAKDM5AKDM4CKDM4EASPH | |
| SCHEMBL4762946 | 0.79 | NAPRT (0.50) | LMNAKDM5AKDM4CKDM4EASPH | |
| SCHEMBL31402348 | 0.79 | KDM5B (0.41) | LMNASMN1; SMN2KDM5AKDM4CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119110800-A | Modulators of interferon gene stimulating factor (STING), compositions and methods | 健道生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| WO-2021262596-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |
| WO-2021007477-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | E-SCAPE BIO, INC. (US) | 2021-01-14 | — | — | WO | disclosed |
| EP-1691610-B1 | METHOD FOR MODIFYING THE BEHAVIOUR OF THRIPS WITH PYRIDINE DERIVATIVES | NZ INST PLANT & FOOD RES LTD (NZ) | 2016-03-09 | — | — | EP | disclosed |
| US-8962003-B2 | Insect behaviour modifying compounds | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) | 2015-02-24 | — | — | US | disclosed |
| US-20080241205-A1 | Insect Behaviour Modifying Compounds | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) | 2008-10-02 | — | — | US | disclosed |
| EP-1691610-A1 | INSECT BEHAVIOUR MODIFYING COMPOUNDS | New Zealand Institute for Crop & Food Research Limited and Plant Research International B.V. (NL) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005046330-A1 | INSECT BEHAVIOUR MODIFYING COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241205-A1 | Insect Behaviour Modifying Compounds | PNMT, ACHE, THOP1 | LMNA 4727/4885SMN1; SMN2 3673/4885KDM5A 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.