Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96272 | 0.93 | LTA4H (0.38) | LTA4HALDH1A1PCSK9MEN1KMT2A | |
| SCHEMBL5964912 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL6542019 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL3542927 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL6717183 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL96871 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL6716782 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL1669437 | 0.91 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL95534 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2NOS3 | |
| SCHEMBL7794055 | 0.79 | SCN5A (0.44) | SMN1; SMN2SIGMAR1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342910-A | Preparation method of monosubstituted cyclopentadiene | 江苏南大光电材料股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117143122-A | Boron-containing organic compound and organic electroluminescent device prepared from same | 江苏三月科技股份有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-116019794-A | Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs | 中国科学院化学研究所 | 2023-04-28 | — | — | CN | claimed |
| CN-114345339-B | Supported binary metal catalyst, preparation method and application thereof | 厦门大学 | 2023-02-21 | — | — | CN | claimed |
| US-20150368236-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-12-24 | — | — | US | claimed |
| EP-2938611-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-11-04 | — | — | EP | claimed |
| WO-2014102244-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-07-03 | — | — | WO | claimed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | claimed |
| US-7897664-B2 | Pneumatic tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2011-03-01 | — | — | US | claimed |
| US-20100076126-A1 | PNEUMATIC TIRE | THE GOODYEAR TIRE & RUBBER COMPANY | 2010-03-25 | — | — | US | claimed |
| US-6500835-B2 | FOR PROPHYLAXIS AND THERAPY OF FIBROSIS INVOLVING EXTRACELLULAR MATRIX DYSBOLISM HAVING A CHYMASE INHIBITOR AS AN EFFECTIVE INGREDIENT; SIDE EFFECT REDUCTION | SUNTORY LIMITED (JP) | 2002-12-31 | — | — | US | claimed |
| EP-1150979-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-11-07 | — | — | EP | claimed |
| US-20010031781-A1 | Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors | ILLIG CARL R (US) | 2001-10-18 | — | — | US | claimed |
| US-6291514-B1 | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-09-18 | — | — | US | claimed |
| WO-2000047578-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-08-17 | — | — | WO | claimed |
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | claimed |
| EP-0087709-A1 | N,N',N\"-triaryl-1,2,3-triaminopropane derivatives, process for their preparation and their use as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-07 | — | — | EP | claimed |
| US-4139530-A | CATIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368236-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | PIR, NT5C, NT5M | LTA4H 196/4885ALDH1A1 2254/4885PCSK9 2456/4885 |
| US-20010031781-A1 | Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors | SERPINE1, PRSS3, PRSS2 | LTA4H 791/4885ALDH1A1 3209/4885PCSK9 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.