SCHEMBL4959463

SCHEMBL4959463

CC(=O)Nc1c(NC(C)=O)c(NC(C)=O)c2c(c1NC(C)=O)C(=O)OC2=O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.38
HSD17B10 Q99714 2/20 0.37
NAPRT Q6XQN6 1/20 0.37
PTGS2 P35354 1/20 0.37
ALDH1A1 P00352 5/20 0.35
CYP1A2 P05177 2/20 0.35
KDM4E B2RXH2 3/20 0.35
CYP2C9 P11712 1/20 0.35
IDO1 P14902 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 2/20 0.34
MAOA P21397 1/20 0.34
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16644022 0.82 ALDH1A1 (0.36) POLBHSD17B10NAPRTPTGS2ALDH1A1
SCHEMBL3828974 0.74 MAOA (0.51) POLBHSD17B10NAPRTPTGS2ALDH1A1
SCHEMBL15580925 0.71 MAOA (0.61) HSD17B10ALDH1A1CYP1A2KDM4ECYP2C9
SCHEMBL303302 0.71 MAOA (0.61) HSD17B10ALDH1A1CYP1A2KDM4ECYP2C9
SCHEMBL4486092 0.71 MAPT (0.41) POLBALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL21749999 0.69 MAOA (0.40) HSD17B10ALDH1A1CYP1A2KDM4ESMN1; SMN2
SCHEMBL15580918 0.68 MAOA (0.39) POLBHSD17B10PTGS2ALDH1A1CYP1A2
SCHEMBL21749940 0.68 ALDH1A1 (0.46) HSD17B10ALDH1A1CYP1A2KDM4ESMN1; SMN2
SCHEMBL21749984 0.68 ALDH1A1 (0.39) HSD17B10ALDH1A1CYP1A2KDM4ESMN1; SMN2
SCHEMBL21750054 0.66 MAOA (0.44) POLBHSD17B10ALDH1A1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR POLB 157/4885HSD17B10 463/4885NAPRT 3704/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT POLB 867/4885HSD17B10 1664/4885NAPRT 2701/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 POLB 434/4885HSD17B10 1057/4885NAPRT 1022/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 POLB 2689/4885HSD17B10 182/4885NAPRT 589/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH POLB 470/4885HSD17B10 2416/4885NAPRT 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.