SCHEMBL4960266

SCHEMBL4960266

O=C(OC(=O)c1cccc2ccc(F)cc12)c1cccc2ccc(F)cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
GAA P10253 2/20 0.44
POLB P06746 1/20 0.44
PLA2G2D Q9UNK4 1/20 0.42
MTNR1A P48039 1/20 0.41
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
IDO1 P14902 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
PLAU P00749 1/20 0.38
TRPV1 Q8NER1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4960629 0.86 PTPN1 (0.45) KMT2AGAAPOLBMEN1CYP1A2
SCHEMBL4104160 0.80 CNR2 (0.44) KMT2APOLBPLA2G2DMTNR1AMEN1
SCHEMBL4960197 0.79 KMT2A (0.44) KMT2AGAAPOLBPLA2G2DMTNR1A
SCHEMBL4959456 0.79 KMT2A (0.47) KMT2AGAAPOLBPLA2G2DMTNR1A
SCHEMBL4960872 0.79 MTNR1A (0.41) KMT2AGAAPOLBPLA2G2DMTNR1A
SCHEMBL137605 0.77 NR4A1 (0.63) KMT2AGAAPOLBMEN1CYP1A2
SCHEMBL29459734 0.77 NR4A1 (0.63) KMT2AGAAPOLBMEN1CYP1A2
SCHEMBL9078976 0.76 KDM4E (0.40) KMT2AGAAPOLBMEN1NR4A1
Potassium SCHEMBL6929965 0.76 NR4A1 (0.61) KMT2AGAAPOLBMEN1CYP1A2
SCHEMBL11422834 0.76 NR4A1 (0.61) KMT2AGAAPOLBMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR KMT2A 3653/4885GAA 797/4885POLB 157/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT KMT2A 3047/4885GAA 234/4885POLB 867/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 KMT2A 2738/4885GAA 721/4885POLB 434/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 KMT2A 1465/4885GAA 14/4885POLB 2689/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH KMT2A 1508/4885GAA 1361/4885POLB 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.