Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962298 | 0.89 | CDC25B (0.46) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL3571420 | 0.84 | MEN1 (0.41) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL3566831 | 0.84 | CES2 (0.41) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL27663621 | 0.81 | MEN1 (0.39) | ALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL697232 | 0.77 | CDC25B (0.63) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL4964197 | 0.74 | DHODH (0.53) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL3566705 | 0.74 | CES2 (0.43) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL27798501 | 0.72 | ALDH1A1 (0.59) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL28745462 | 0.72 | CDC25B (0.57) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL3573848 | 0.72 | LMNA (0.44) | ALDH1A1KDM4EKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064748-A1 | Substituted enaminones, their derivatives and uses thereof | OXFORD FINANCE CORPORATION | 2008-03-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064748-A1 | Substituted enaminones, their derivatives and uses thereof | GABRB2, GABRB1, GABRB3 | CDC25B 4622/4885ALDH1A1 423/4885KDM4E 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.