Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582955 | 0.82 | PARP1 (0.37) | PARP1NPSR1PPOXCASP3GSK3B | |
| SCHEMBL2312949 | 0.81 | PARP1 (0.39) | PARP1NPSR1POLBPPOXCASP3 | |
| SCHEMBL11615863 | 0.81 | SRD5A1 (0.44) | PARP1NPSR1MEN1POLBMAPT | |
| SCHEMBL5333323 | 0.74 | IMPDH2 (0.49) | NPSR1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL2651667 | 0.73 | KDM4E (0.40) | PARP1TDP1NPSR1CYP3A4MEN1 | |
| SCHEMBL9355397 | 0.73 | MAOA (0.56) | TDP1NPSR1CYP3A4MEN1POLB | |
| SCHEMBL767501 | 0.73 | PARP1 (0.50) | PARP1TDP1NPSR1CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL10885430 | 0.73 | IMPDH2 (0.47) | NPSR1MEN1MAPTKMT2AIMPDH2 | |
| SCHEMBL845635 | 0.72 | IMPDH2 (0.53) | NPSR1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL4552739 | 0.72 | PIM1 (0.36) | PARP1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966335-A2 | PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | claimed |
| WO-2007070724-A2 | PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-06-21 | — | — | WO | claimed |
| EP-0696580-B1 | Carbonate and urethane groups containing tertiary amines and their use as catalyst in the preparation of polyurethanes | BAYER AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0696580-A2 | Carbonate and urethane groups containing tertiary amines and their use as catalyst in the preparation of polyurethanes | BAYER AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| EP-0369526-B1 | Nitromethylene compounds, their preparation and their use as pesticides | SHELL INT RESEARCH (NL) | 1995-07-26 | — | — | EP | disclosed |