SCHEMBL49837

SCHEMBL49837

[O]c1ccccc1Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
KMT2A Q03164 1/20 0.54
TSHR P16473 2/20 0.52
LTA4H P09960 1/20 0.52
CTNNB1 P35222 1/20 0.50
HTT P42858 2/20 0.46
HRH1 P35367 1/20 0.45
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSPO P30536 1/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
RIPK1 Q13546 1/20 0.44
HPGD P15428 1/20 0.44
TLR4 O00206 1/20 0.43
TLR2 O60603 1/20 0.43
KDM1A O60341 2/20 0.42
HTR1A P08908 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16635252 0.84 L3MBTL1 (0.49) LMNAGAAKMT2AHTTALDH1A1
SCHEMBL2186316 0.84 CA12 (0.38) LMNAGAAKMT2ATSHRLTA4H
SCHEMBL2149766 0.82 HTR2A (0.53) LMNAGAAKMT2AHTTALDH1A1
SCHEMBL2091702 0.82 KMT2A (0.47) LMNAGAAKMT2ATSHRLTA4H
SCHEMBL10753674 0.82 ALDH1A1 (0.39) LMNAGAAKMT2ATSHRCTNNB1
SCHEMBL5538018 0.82 SLC6A2 (0.50) LMNAGAAKMT2ATSHRCTNNB1
SCHEMBL9046668 0.82 HTR2A (0.54) LMNAKMT2AHTTALDH1A1MAPK1
SCHEMBL2097326 0.82 PTGS2 (0.49) LMNAGAAKMT2ATSHRLTA4H
SCHEMBL51822 0.81 LTA4H (0.69) LMNAGAAKMT2ATSHRLTA4H
SCHEMBL9636814 0.81 DPP4 (0.49) LMNAGAAKMT2ATSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US claimed
EP-3681281-A1 COMPOSITIONS AND METHODS FOR CROP DEFENSE AdvanSix Resins & Chemicals LLC (US) 2020-07-22 EP claimed
WO-2019055610-A1 COMPOSITIONS AND METHODS FOR CROP DEFENSE ADVANSIX RESINS & CHEMICALS LLC (US) 2019-03-21 WO claimed
US-20190075787-A1 COMPOSITIONS AND METHODS FOR CROP DEFENSE TRUIST BANK, AS ADMINISTRATIVE AGENT 2019-03-14 US claimed
US-9392785-B2 Use of esteramides as solvents, novel esteramides and process for preparing esteramides RHODIA OPERATIONS (FR) 2016-07-19 US claimed
US-7547749-B2 Triazine compounds, polymers comprising triazine structural units, and method SABIC INNOVATIVE PLATICS IP B.V. (NL) 2009-06-16 US claimed
US-20080097040-A1 TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND METHOD GENERAL ELECTRIC COMPANY (US) 2008-04-24 US claimed
US-20070238615-A1 Liquid Formulations in Crop Protection and Their Use BAYER CROPSCIENCE GMBH (DE) 2007-10-11 US claimed
US-20050192411-A1 Triazine compounds, polymers comprising triazine structural units, and method GENERAL ELECTRIC CO. 2005-09-01 US claimed
EP-1423372-A2 TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS GENERAL ELECTRIC COMPANY (US) 2004-06-02 EP claimed
EP-0170905-A1 alpha-acyloximino-alkane-phosphonic(and -phosphinic) acid esters, their preparation and their use in plant protection HOECHST AKTIENGESELLSCHAFT (DE) 1986-02-12 EP claimed
EP-0163236-A2 Benzoxazolyl and benzothiazolyl aminoacids, their preparation and their use in the preservation of plants HOECHST AKTIENGESELLSCHAFT (DE) 1985-12-04 EP claimed
EP-0149034-A2 Regulation of plant metalbolism by alpha,beta- or beta,gamma-unsaturated carboxylic acids or derivatives thereof TEIJIN LIMITED (JP) 1985-07-24 EP claimed
EP-0118685-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-19 EP claimed
EP-0117412-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-05 EP claimed
US-4360375-A Phenoxyphenoxy unsaturated derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1982-11-23 US claimed
US-4263040-A Phenoxyphenoxy unsaturated derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1981-04-21 US claimed
EP-0010232-A1 Herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1980-04-30 EP claimed
US-4031073-A Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof CIBA-GEIGY CORPORATION (US) 1977-06-21 US claimed
US-3965218-A INSECTICIDE CHEVRON RESEARCH COMPANY (US) 1976-06-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190075787-A1 COMPOSITIONS AND METHODS FOR CROP DEFENSE CAPN9, CAPRIN1, CAPN1 LMNA 2107/4885GAA 2169/4885KMT2A 4073/4885
US-20070238615-A1 Liquid Formulations in Crop Protection and Their Use FADS2, FASN, ACSS2 LMNA 1345/4885GAA 379/4885KMT2A 1211/4885
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method ASH2L, MLLT1, FRG1 LMNA 505/4885GAA 3952/4885KMT2A 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.