Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105049 | 0.77 | PTGS2 (0.47) | LMNAPTPN1PTGS2PPARGPPARD | |
| SCHEMBL4104338 | 0.68 | HMGCR (0.44) | LMNAHIF1APTPN1ACLYACACA | |
| SCHEMBL29934469 | 0.64 | ACLY (0.47) | PTPN1PTGS2ACLYACACA | |
| SCHEMBL29934458 | 0.62 | HSD11B1 (0.49) | MEN1KMT2APTPN1PTGS2ACLY | |
| SCHEMBL3479594 | 0.61 | ACLY (0.65) | CYP3A4LMNAMAPTHIF1APTGS2 | |
| SCHEMBL332666 | 0.60 | CDC25A (0.51) | MEN1LMNAKMT2APTPN1EBP | |
| SCHEMBL4212762 | 0.60 | PTPN1 (0.53) | LMNAHIF1APTPN1 | |
| SCHEMBL13642557 | 0.58 | GPBAR1 (0.48) | CYP3A4MEN1LMNAMAPTKMT2A | |
| SCHEMBL13642752 | 0.58 | GPBAR1 (0.48) | CYP3A4MEN1LMNAMAPTKMT2A | |
| SCHEMBL9153127 | 0.56 | LMNA (0.49) | MEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993579-A2 | A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION/TREATMENT OF BONE DISORDERS AND A PROCESS FOR THE PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007099432-A2 | PHARMACEUTICAL COMPOSITION CONTAINING BUTEA ISOFLAVONES FOR THE PREVENTION /TREATMENT OF BONE DISORDERS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-07 | — | — | WO | disclosed |