Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 2/20 | 0.32 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985464 | 0.77 | CYP3A4 (0.33) | PTGS2PTPN1ACLYACACAPPARG | |
| SCHEMBL4104338 | 0.74 | HMGCR (0.44) | PTPN1ACLYACACAHMGCRGPBAR1 | |
| SCHEMBL29934469 | 0.69 | ACLY (0.47) | PTGS2PTPN1CETPNR1H4ACLY | |
| SCHEMBL29934458 | 0.67 | HSD11B1 (0.49) | PTGS2PTPN1CETPNR1H4ACLY | |
| SCHEMBL27494595 | 0.65 | GPBAR1 (0.53) | PTPN1NR1H4GPBAR1LMNA | |
| SCHEMBL3479596 | 0.65 | ACLY (0.65) | PTGS2ACLYACACAHMGCRLMNA | |
| SCHEMBL3479594 | 0.65 | ACLY (0.65) | PTGS2ACLYACACAHMGCRLMNA | |
| SCHEMBL28831684 | 0.64 | HMGCR (0.54) | ACLYACACAHMGCRLMNAEBP | |
| SCHEMBL12036681 | 0.64 | POLA1 (0.49) | — | |
| SCHEMBL4735768 | 0.61 | CDC25A (0.51) | GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221690-A1 | Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221690-A1 | Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof | SOST, BPGM, PTMS | PTGS2 3109/4885PTPN1 2716/4885ACHE 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.