SCHEMBL499071

SCHEMBL499071

O=S(=O)(O)c1ccc(-c2cc3cc4nc(cc5ccc(cc6nc(cc2[nH]3)C=C6)[nH]5)C=C4)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 1/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.39
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ THRB P10828 1/20 0.35
▸ APEX1 P27695 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ ADORA2B P29275 6/20 0.35
▸ ADORA2A P29274 4/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ GLA P06280 3/20 0.35
▸ HPGD P15428 3/20 0.35
▸ HSD17B10 Q99714 3/20 0.35
▸ ADORA3 P0DMS8 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ NFKB1 P19838 1/20 0.35
▸ ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28890943 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
Water SCHEMBL28884510 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
SCHEMBL31463625 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
SCHEMBL11348270 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
Zinc Ion SCHEMBL31253325 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
SCHEMBL28414549 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
Hydrochloric Acid SCHEMBL8585886 0.99 ENPP2 (0.42) ENPP2HDAC6MEN1KMT2ATHRB
Hydrochloric Acid SCHEMBL28680099 0.97 ENPP2 (0.41) ENPP2HDAC6MEN1KMT2ATHRB
Water SCHEMBL28814730 0.97 ENPP2 (0.41) ENPP2HDAC6MEN1KMT2ATHRB
Hydrochloric Acid SCHEMBL5967794 0.97 ENPP2 (0.41) ENPP2HDAC6MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113504190-B Rapid detection method and reagent for trace copper in water quality 广东环凯生物技术有限公司 2024-06-25 — — CN claimed
WO-2024095177-A1 MANGANESE BIFUNCTIONAL CHELATING AGENT CONJUGATION PLATFORM FOR TARGETED MR IMAGING THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-05-10 — — WO claimed
US-11892401-B2 Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-02-06 — — US claimed
CN-117482256-A Dual-mode nano contrast agent and preparation method and application thereof 浙大城市学院 2024-02-02 — — CN claimed
CN-117358309-A Porphyrin/metal sulfide composite photocatalyst and preparation method thereof 中国石油大学(华东) 2024-01-09 — — CN claimed
US-20230310404-A1 COMPOSITIONS AND METHODS FOR REDUCING LAMINITIS OF AN ANIMAL HOOF EQUINE PODIATRY SOLUTIONS LLC (US) 2023-10-05 — — US claimed
CN-116759670-A Porphyrin water-based zinc ion battery electrolyte additive and application thereof 东北师范大学 2023-09-15 — — CN claimed
US-20230115432-A1 Methods and Apparatuses for Early Diagnosis of Lung Infection Acuity DIAGNOSE EARLY, INC. 2023-04-13 — — US claimed
EP-4127212-A1 METHODS AND APPARATUSES FOR EARLY DIAGNOSIS OF LUNG INFECTION ACUITY Diagnose Early, Inc. (US) 2023-02-08 — — EP claimed
CN-115487873-A Non-noble metal/porphyrin-based photocatalyst and preparation method thereof 中国石油大学(华东) 2022-12-20 — — CN claimed
US-20040202610-A1 Method and apparatus including use of metalloporphyrins for subsequent optimization of radiosurgery and radiotherapy ADAIR EDWIN L (US) 2004-10-14 — — US claimed
US-20040116500-A1 Methods and compositions to treat lung diseases SAKALOSKY GEORGE P (US) 2004-06-17 — — US claimed
US-6660762-B2 Administering porphyrin compound; respiratory system disorders SAKALOSKY GEORGE P (US) 2003-12-09 — — US claimed
EP-1360221-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-12 — — EP claimed
US-20030004204-A1 Methods and compositions to treat lung diseases SAKALOSKY GEORGE P (US) 2003-01-02 — — US claimed
WO-2002055584-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 — — WO claimed
US-6291631-B1 CONTACTING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE POLYMERIZATION CATALYST UNDER POLYCARBONATE MELT POLYMERIZATION CONDITIONS GENERAL ELECTRIC COMPANY 2001-09-18 — — US claimed
EP-1068272-A2 IMPROVED METHOD OF MAKING SULFANATOPHENYL SUBSTITUTED PORPHINES Kimberly-Clark Worldwide, Inc. (US) 2001-01-17 — — EP claimed
WO-1999036476-A2 IMPROVED METHOD OF MAKING SULFANATOPHENYL SUBSTITUTED PORPHINES KIMBERLY-CLARK WORLWIDE, INC. (US) 1999-07-22 — — WO claimed
US-5414080-A Porphyrin-metallic complex intercalated layered double hydroxides BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1995-05-09 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11892401-B2 Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases SI, FABP2, FABP6 ENPP2 424/4885HDAC6 2445/4885MEN1 3734/4885
US-20030004204-A1 Methods and compositions to treat lung diseases PPOX, BPGM, CLN6 ENPP2 20/4885HDAC6 2849/4885MEN1 1335/4885
US-20230310404-A1 COMPOSITIONS AND METHODS FOR REDUCING LAMINITIS OF AN ANIMAL HOOF COX15, HMOX2, HMOX1 ENPP2 3251/4885HDAC6 964/4885MEN1 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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