SCHEMBL5002480

SCHEMBL5002480

CCN(CC)CCOC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
KDM4E B2RXH2 2/20 0.38
TSHR P16473 1/20 0.38
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
LMNA P02545 2/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
SCN5A Q14524 1/20 0.33
SCN9A Q15858 1/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
EBP Q15125 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
LTA4H P09960 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23977797 0.88 MEN1 (0.33) MEN1KMT2APOLBKDM4ETSHR
SCHEMBL12448059 0.86 MEN1 (0.45) MEN1KMT2APOLBKDM4ETSHR
SCHEMBL12120256 0.86 KDM4E (0.33) KDM4E
SCHEMBL12028002 0.85 KDM4E (0.42) MEN1KMT2APOLBKDM4ETSHR
SCHEMBL25567922 0.84 MEN1 (0.31) MEN1KMT2APOLBKDM4ETSHR
SCHEMBL14920988 0.84 MEN1 (0.41) MEN1KMT2APOLBKDM4ETSHR
SCHEMBL26711220 0.83 MEN1 (0.31) MEN1KMT2APOLB
SCHEMBL24701914 0.82 ALDH1A1 (0.33) KDM4EALDH1A1SMN1; SMN2
SCHEMBL7079430 0.82 MEN1 (0.40) MEN1KMT2APOLBKDM4ETSHR
SCHEMBL20438419 0.81 KDM4E (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8298744-B2 Coating material for photoresist pattern and method of forming fine pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-30 US claimed
US-20080286684-A1 COATING MATERIAL FOR PHOTORESIST PATTERN AND METHOD OF FORMING FINE PATTERN USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-20 US claimed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
WO-2024100139-A1 USE OF IFN-I ACTIVITY AS A BIOMARKER FOR TLR INHIBITOR TREATMENT MERCK PATENT GMBH (DE) 2024-05-16 WO disclosed
US-20240018655-A1 METHOD OF PRODUCING THIN-FILM ADEKA CORPORATION (JP) 2024-01-18 US disclosed
US-20230148005-A1 MACROCYCLIC COMPOUNDS AND USES THEREOF THESEUS PHARMACEUTICALS, INC. 2023-05-11 US disclosed
US-20230148005-A1 MACROCYCLIC COMPOUNDS AND USES THEREOF THESEUS PHARMACEUTICALS, INC. 2023-05-11 US disclosed
US-20230145822-A1 SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN FONDAZIONE TELETHON (IT) 2023-05-11 US disclosed
US-20230018729-A1 TL1A PATIENT SELECTION METHODS, SYSTEMS, AND DEVICES PROMETHEUS BIOSCIENCES, INC. 2023-01-19 US disclosed
US-11377441-B2 Covalent inhibitors of KRAS ARAXES PHARMA LLC (US) 2022-07-05 US disclosed
US-7468371-B2 Tricyclic pyrazole kinase inhibitors ABBOTT LABORATORIES INC. (US) 2008-12-23 US disclosed
US-7468371-B2 Tricyclic pyrazole kinase inhibitors ABBOTT LABORATORIES INC. (US) 2008-12-23 US disclosed
US-20080286684-A1 COATING MATERIAL FOR PHOTORESIST PATTERN AND METHOD OF FORMING FINE PATTERN USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-20 US disclosed
US-20080260803-A1 Producing eye insertable drug delivery agent; extruding active ingredient with polyvinyl alcohol free biodegradable polymer ALLERGAN,INC. (US) 2008-10-23 US disclosed
US-20080254096-A1 Using polyvinyl alcohol free biodegradable polymer matrix; reducing side effects, invasive procedures and high transient concentrations; glaucoma, proliferative vitreoretinopathy ALLERGAN,INC (US) 2008-10-16 US disclosed
US-20080241252-A1 METHODS AND COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION TO TREAT OCULAR CONDITIONS ALLERGAN, INC. (US) 2008-10-02 US disclosed
US-20080241252-A1 METHODS AND COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION TO TREAT OCULAR CONDITIONS ALLERGAN, INC. (US) 2008-10-02 US disclosed
US-7414054-B2 3-(arylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors ALLERGAN, INC. (US) 2008-08-19 US disclosed
US-7279489-B2 Compounds and methods for modulation of estrogen receptors SIGNAL PHARMACEUTICALS, LLC (US) 2007-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148005-A1 MACROCYCLIC COMPOUNDS AND USES THEREOF EGFR, ERBB2, ERBB3 MEN1 1792/4885KMT2A 2433/4885POLB 3343/4885
US-11377441-B2 Covalent inhibitors of KRAS KRAS, NRAS, HRAS MEN1 148/4885KMT2A 445/4885POLB 653/4885
US-20230018729-A1 TL1A PATIENT SELECTION METHODS, SYSTEMS, AND DEVICES TLL1, TLN1, TSG101 MEN1 1295/4885KMT2A 292/4885POLB 735/4885
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TP53, HRAS, KRAS MEN1 752/4885KMT2A 2941/4885POLB 2036/4885
US-20080254096-A1 Using polyvinyl alcohol free biodegradable polymer matrix; reducing side effects, invasive procedures and high transient concentrations; glaucoma, proliferative vitreoretinopathy VEGFA, PTK2, KDR MEN1 1851/4885KMT2A 1220/4885POLB 2170/4885
US-20240018655-A1 METHOD OF PRODUCING THIN-FILM RTF1, GIGYF2, HAO2 MEN1 933/4885KMT2A 2569/4885POLB 2693/4885
US-20080241252-A1 METHODS AND COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION TO TREAT OCULAR CONDITIONS FLT1, JAK1, KDR MEN1 4086/4885KMT2A 858/4885POLB 2270/4885
US-20230145822-A1 SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN PRNP, PPIE, PPIC MEN1 3669/4885KMT2A 4350/4885POLB 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.