SCHEMBL500576

SCHEMBL500576

CCC(=CC(F)(F)F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.35
GRIK1 P39086 3/20 0.34
ABAT P80404 1/20 0.32
EPHX2 P34913 2/20 0.32
PPARG P37231 1/20 0.32
GRIK2 Q13002 2/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL500575 1.00 FFAR3 (0.35) FFAR3GRIK1ABATEPHX2PPARG
Hydrochloric Acid SCHEMBL27563634 0.98 GRIK1 (0.33) FFAR3GRIK1ABATEPHX2PPARG
SCHEMBL11233789 0.79 EPHX2 (0.32) GRIK1EPHX2PPARG
SCHEMBL14723746 0.78 GRIK1 (0.53) FFAR3GRIK1EPHX2PPARGGRIK2
SCHEMBL9418732 0.78 GRIK1 (0.53) FFAR3GRIK1EPHX2PPARGGRIK2
SCHEMBL8828770 0.77 ABAT (0.34) FFAR3GRIK1ABAT
SCHEMBL5359965 0.77 THRB (0.34) GRIK1
SCHEMBL2418566 0.76 FFAR3 (0.35) FFAR3GRIK1GRIK2KDM4ETSHR
SCHEMBL2418563 0.76 FFAR3 (0.35) FFAR3GRIK1GRIK2KDM4ETSHR
SCHEMBL8152582 0.76 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999333-A Modified fluorosilicone acrylate resin, antifouling antibacterial coating and preparation method thereof 上海沪正实业有限公司 2022-02-01 CN claimed
CN-113653486-A Slow-release type long-acting tracer and preparation method thereof 捷贝通石油技术集团股份有限公司 2021-11-16 CN claimed
US-20240043593-A1 Fluorine-Containing Polymer CENTRAL GLASS COMPANY, LIMITED (JP) 2024-02-08 US disclosed
WO-2022124183-A1 FLUORINE-CONTAINING POLYMER セントラル硝子株式会社 2022-06-16 WO disclosed
CN-113999333-A Modified fluorosilicone acrylate resin, antifouling antibacterial coating and preparation method thereof 上海沪正实业有限公司 2022-02-01 CN disclosed
EP-3215476-B1 METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS LONZA AG (CH) 2018-02-28 EP disclosed
US-9809596-B1 Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis LONZA LTD. (CH) 2017-11-07 US disclosed
EP-3215476-A1 METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS Lonza Ltd (CH) 2017-09-13 EP disclosed
US-9599758-B2 Optical reflective film and optical reflector using the same Konica Minolta, Inc. (JP) 2017-03-21 US disclosed
WO-2016071425-A1 METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS LONZA LTD (CH) 2016-05-12 WO disclosed
US-20150285974-A1 OPTICAL REFLECTIVE FILM AND OPTICAL REFLECTOR USING THE SAME Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-6476224-B2 N-(4-CYANO-2,5- DIFLUORO-PHENYL) -3-(DIMETHYLAMINOCARBONYLAMINO)-4,4,4-TRIFLUORO-2-BUTENAMIDE AND 1,2-DIMETHOXYETHANE ARE HEATED TO FORM AR(ALK)YL URACIL COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 2002-11-05 US disclosed
US-20020022727-A1 Method for producing ar(alk)yluraciles, novel corresponding intermediate products and method for producing said intermediate products GALLENKAMP BERND (DE) 2002-02-21 US disclosed
US-20010044539-A1 Heterobicyclic and tricyclic nitric oxide synthase inhibitors HANSEN DONALD W (US) 2001-11-22 US disclosed
US-6225470-B1 HEATING SUBSTITUTED AMINOALKENAMIDES IN PRESENCE OF DILUENTS TO PRODUCE AR(ALK)YLURACIL BAYER AKTIENGESELLSCHAFT (DE) 2001-05-01 US disclosed
EP-1086108-A1 HETEROBICYCLIC AND TRICYCLIC NITRIC OXIDE SYNTHASE INHIBITORS G.D. Searle & Co. (US) 2001-03-28 EP disclosed
WO-1999064426-A1 HETEROBICYCLIC AND TRICYCLIC NITRIC OXIDE SYNTHASE INHIBITORS G.D. SEARLE & CO. (US) 1999-12-16 WO disclosed
US-5629264-A 2-aryl-5,6-dihydropyrimidinones and herbicidal use thereof ROHM AND HAAS COMPANY (US) 1997-05-13 US disclosed
EP-0733622-A1 2-Aryl-5,6-dihydropyrimidinones and herbicidal use thereof ROHM AND HAAS COMPANY (US) 1996-09-25 EP disclosed
EP-0021883-A2 N-acyl-amino acid derivatives and pharmaceutical compositions containing them, intermediates and starting compounds MERRELL TORAUDE ET COMPAGNIE (FR) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010044539-A1 Heterobicyclic and tricyclic nitric oxide synthase inhibitors NOS1, NOS2, NOS3 FFAR3 1855/4885GRIK1 1900/4885ABAT 137/4885
US-20020022727-A1 Method for producing ar(alk)yluraciles, novel corresponding intermediate products and method for producing said intermediate products ALK, ALKBH5, ALKBH1 FFAR3 828/4885GRIK1 2930/4885ABAT 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.