Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010707 | 0.82 | HSD11B1 (0.60) | HSD11B1HTTHTR2AHTR2CSLC6A4 | |
| SCHEMBL5012972 | 0.68 | HTR2A (0.53) | HTTHTR2AHTR2CSLC6A4TP53 | |
| SCHEMBL4822958 | 0.67 | ALDH1A1 (0.49) | HTTHTR2AHTR2CSLC6A4ALDH1A1 | |
| SCHEMBL533000 | 0.66 | ACLY (0.68) | HTTHTR2AHTR2CSLC6A4TP53 | |
| SCHEMBL6177741 | 0.66 | AR (0.51) | — | |
| SCHEMBL5010583 | 0.66 | HTR2A (0.81) | HTR2AHTR2CSLC6A4TP53TAS2R14 | |
| SCHEMBL5006633 | 0.65 | ALDH1A1 (0.64) | HSD11B1HTTHTR2CALDH1A1TAS2R14 | |
| SCHEMBL5009435 | 0.64 | ALDH1A1 (0.56) | HTTHTR2AHTR2CSLC6A4ALDH1A1 | |
| SCHEMBL8296687 | 0.63 | HSD11B1 (1.00) | HSD11B1HTTALDH1A1PGR | |
| SCHEMBL4175286 | 0.63 | AR (0.48) | SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | claimed |
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |