Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010703 | 0.82 | HSD11B1 (0.46) | HSD11B1HTTHTR2AHTR2CSLC6A4 | |
| SCHEMBL8296687 | 0.75 | HSD11B1 (1.00) | HSD11B1HTTMAPTPOLBPGR | |
| SCHEMBL5012972 | 0.69 | HTR2A (0.53) | HTTHTR2AHTR2CSLC6A4MAPT | |
| SCHEMBL8389644 | 0.69 | HTR1D (0.57) | HSD11B1MAPTMRGPRX4L3MBTL1 | |
| SCHEMBL8390609 | 0.69 | LMNA (0.57) | HSD11B1MAPTMRGPRX4L3MBTL1 | |
| SCHEMBL11508991 | 0.68 | TLR8 (0.52) | HSD11B1SLC6A4MAPTMRGPRX4L3MBTL1 | |
| SCHEMBL533000 | 0.68 | ACLY (0.68) | HTTHTR2AHTR2CSLC6A4TP53 | |
| SCHEMBL5010583 | 0.67 | HTR2A (0.81) | HTR2AHTR2CSLC6A4MAPTTP53 | |
| SCHEMBL8703660 | 0.67 | HSD11B1 (0.54) | HSD11B1HTR2ASLC6A4MAPTPOLB | |
| SCHEMBL14568177 | 0.67 | ALDH1A1 (0.46) | HSD11B1HTTMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | claimed |
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |