Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15694063 | 0.87 | DGKA (0.39) | RAB9ANAAADGKAALDH1A1LMNA | |
| SCHEMBL522692 | 0.86 | ALDH1A1 (0.52) | NAAADGKAALDH1A1HCAR2LMNA | |
| SCHEMBL15876208 | 0.86 | NAAA (0.40) | RAB9ANAAADGKAALDH1A1HCAR2 | |
| Ammonia Solution, Strong SCHEMBL27789119 | 0.85 | ALDH1A1 (0.50) | NAAADGKAALDH1A1HCAR2LMNA | |
| SCHEMBL13602569 | 0.85 | NAAA (0.61) | NAAADGKAALDH1A1HCAR2TSHR | |
| SCHEMBL12673152 | 0.84 | NAAA (0.48) | RAB9ANAAADGKAALDH1A1LMNA | |
| SCHEMBL31058603 | 0.84 | NAAA (0.39) | RAB9ANAAADGKAALDH1A1HCAR2 | |
| SCHEMBL20260349 | 0.83 | NAAA (0.64) | NAAADGKAALDH1A1HCAR2LMNA | |
| SCHEMBL28486138 | 0.83 | NAAA (0.64) | NAAADGKAALDH1A1HCAR2LMNA | |
| SCHEMBL18856234 | 0.83 | NAAA (0.64) | NAAADGKAALDH1A1HCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2023-08-24 | — | — | US | disclosed |
| US-11649214-B2 | Inhibitors of the notch transcriptional activation complex kinase (“NACK”) and methods for use of the same | UNIVERSITY OF MIAMI (US) | 2023-05-16 | — | — | US | disclosed |
| US-20210101878-A1 | Cannabinergic Compounds And Uses Thereof | NORTHEASTERN UNIVERSITY | 2021-04-08 | — | — | US | disclosed |
| CN-109952360-A | Quantum dot dispersion liquid, self-luminous photosensitive polymer combination, the colour filter and image display device manufactured using it | 东友精细化工有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109810589-A | Light converts resin combination, light conversion layer folds substrate and image display device | 东友精细化工有限公司 | 2019-05-28 | — | — | CN | disclosed |
| US-9957290-B2 | Derivatives of amphotericin B | SFUNGA THERAPEUTICS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160304548-A1 | Derivatives of Amphotericin B | ELION THERAPEUTICS, INC. | 2016-10-20 | — | — | US | disclosed |
| CN-105021602-A | Dimethyl sulfide detection reagent, and preparation method thereof | DONGCHEN LEADER TESTING CO LTD | 2015-11-04 | — | — | CN | disclosed |
| US-8324273-B2 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | XENOPORT, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-7402690-B2 | Chain transfer agents for raft polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2008-07-22 | — | — | US | disclosed |
| US-20080171789-A1 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | XENOPORT, INC. | 2008-07-17 | — | — | US | disclosed |
| EP-1492796-B1 | SUBSTITUTED AMINO ISOXAZOLINE DERIVATIVES AND THEIR USE AS ANTI-DEPRESSANTS. | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-05 | — | — | EP | disclosed |
| US-7265103-B2 | Substituted amino isoxazoline derivatives and their use as anti-depressants | JANSSEN PHARMACEUTICA NV. (BE) | 2007-09-04 | — | — | US | disclosed |
| US-7265103-B2 | Substituted amino isoxazoline derivatives and their use as anti-depressants | JANSSEN PHARMACEUTICA NV. (BE) | 2007-09-04 | — | — | US | disclosed |
| US-20070123670-A1 | Chain transfer agents for raft polymerization in aqueous media | MCCORMICK CHARLES L | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | BCAT1, PCMT1, LTN1 | RAB9A 2049/4885NAAA 2509/4885DGKA 4291/4885 |
| US-20160304548-A1 | Derivatives of Amphotericin B | C9, ERG28, AMPD3 | RAB9A 1090/4885NAAA 71/4885DGKA 1622/4885 |
| US-11649214-B2 | Inhibitors of the notch transcriptional activation complex kinase (“NACK”) and methods for use of the same | NOTCH1, CHUK, CBFB | RAB9A 3062/4885NAAA 1769/4885DGKA 177/4885 |
| US-20210101878-A1 | Cannabinergic Compounds And Uses Thereof | CNR2, CNR1, GPR18 | RAB9A 1423/4885NAAA 447/4885DGKA 699/4885 |
| US-20080171789-A1 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | COMT, PARK7, DDT | RAB9A 1705/4885NAAA 557/4885DGKA 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.