SCHEMBL50124

SCHEMBL50124

Nc1cccc(-c2conn2)c1N

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CD44 P16070 1/20 0.33
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ATAD2 Q6PL18 1/20 0.30
IDO1 P14902 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5152908 0.85 ALDH1A1 (0.52) ALDH1A1L3MBTL1KDM4ENPC1GAA
SCHEMBL20379117 0.72 ALDH1A1 (0.34) ALDH1A1L3MBTL1CD44KDM4ENPC1
SCHEMBL29483286 0.70 CNR2 (0.43) ALDH1A1NPC1HPGDRAB9ASMN1; SMN2
SCHEMBL560128 0.70 ALDH1A1 (0.56) ALDH1A1L3MBTL1CD44HPGDSMN1; SMN2
SCHEMBL7736978 0.69
SCHEMBL6348373 0.69 CASP3 (0.35)
SCHEMBL6135309 0.69 GPR55 (0.39) ALDH1A1NPC1HPGDRAB9ASMN1; SMN2
SCHEMBL2679546 0.69 RAB9A (0.48) ALDH1A1L3MBTL1KDM4ENPC1GAA
SCHEMBL4954846 0.69 IDO1 (0.43) ALDH1A1KDM4ENPC1GAAHPGD
SCHEMBL5575870 0.68 NPC1 (0.55) ALDH1A1L3MBTL1CD44KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164252-A1 ISOTHERMAL NUCLEIC ACID DETECTION ASSAYS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-08-31 WO claimed
CN-109342381-A A kind of fluorescent dyeing reagent 广州往圣生物科技有限公司 2019-02-15 CN claimed
US-9915665-B2 High-throughput system and method for identifying antibodies having specific antigen binding activities ABBVIE INC. (US) 2018-03-13 US claimed
WO-2017027062-A1 PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2017-02-16 WO claimed
US-20170044593-A1 PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2017-02-16 US claimed
EP-2938636-A2 HIGH-THROUGHPUT SYSTEM AND METHOD FOR IDENTIFYING ANTIBODIES HAVING SPECIFIC ANTIGEN BINDING ACTIVITIES AbbVie Inc. (US) 2015-11-04 EP claimed
US-20140243228-A1 HIGH-THROUGHPUT SYSTEM AND METHOD FOR IDENTIFYING ANTIBODIES HAVING SPECIFIC ANTIGEN BINDING ACTIVITIES ABBVIE, INC. (US) 2014-08-28 US claimed
US-8816095-B2 Na channels, disease, and related assays and compositions GEORGETOWN UNIVERSITY (US) 2014-08-26 US claimed
WO-2014106004-A2 HIGH-THROUGHPUT SYSTEM AND METHOD FOR IDENTIFYING ANTIBODIES HAVING SPECIFIC ANTIGEN BINDING ACTIVITIES ABBVIE, INC. (US) 2014-07-03 WO claimed
US-20140024137-A1 METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS NUBAD LLC 2014-01-23 US claimed
US-20130344588-A1 DEVICES AND METHODS FOR CONCENTRATION AND ANALYSIS OF FLUIDS MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) 2013-12-26 US claimed
WO-2013070943-A2 SMALL MOLECULE SCREEN FOR INHIBITORS OF NFAT:AP-1:DNA INTERACTIONS CHILDREN'S MEDICAL CENTER CORPORATION (US) 2013-05-16 WO claimed
EP-2330908-A1 FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER Georgetown University (US) 2011-06-15 EP claimed
WO-2010019967-A1 FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER GEORGETOWN UNIVERSITY (US) 2010-02-18 WO claimed
WO-2026107198-A1 ANTIBODY BIOMARKER TO DIAGNOSE IDIOPATHIC INFLAMMATORY MYOPATHIES OHIO STATE INNOVATION FOUNDATION (US) 2026-05-21 WO disclosed
US-20260125675-A1 DOWNREGULATING TROLLS USING NOVEL ANTISENSE OLIGONUCLEOTIDES TO OVERCOME RESISTANCE TO CHEMOTHERAPY H LEE MOFFITT CANCER CENTER AND RESEARCH INST INC (US) 2026-05-07 US disclosed
EP-4731758-A2 ANTIGEN-SPECIFIC T CELL RECEPTORS AND CHIMERIC ANTIGEN RECEPTORS, AND METHODS OF USE IN IMMUNE SIGNALING MODULATION FOR CANCER IMMUNOTHERAPY The Methodist Hospital (US) 2026-04-29 EP disclosed
EP-0478682-A1 DETECTION OF FUNGAL GROWTH. ASSURANCE COMPAGNIET BALTICA A (DK) 1992-04-08 EP disclosed
WO-1990015879-A1 DETECTION OF FUNGAL GROWTH ASSURANCE-COMPAGNIET BALTICA A/S (DK) 1990-12-27 WO disclosed
US-4361638-A AMORPHOUS SILICON AND CARBON BASE MATERIAL DOPED WITH HYDROGEN AND FLUORINE FUJI PHOTO FILM CO., LTD. (JP) 1982-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044593-A1 PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA DPEP1, MRPL21, RCE1 ALDH1A1 701/4885L3MBTL1 284/4885CD44 3676/4885
US-20260125675-A1 DOWNREGULATING TROLLS USING NOVEL ANTISENSE OLIGONUCLEOTIDES TO OVERCOME RESISTANCE TO CHEMOTHERAPY PDCD1LG2, TRMT1L, TTLL12 ALDH1A1 3647/4885L3MBTL1 13/4885CD44 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.