SCHEMBL5014126

SCHEMBL5014126

c1ccc(-c2ccc(-c3conn3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.44
NPC1 O15118 6/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GABRA1 P14867 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL637900 0.96 RAB9A (0.42) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL28271180 0.89 ENPP3 (0.31) ENPP3ENPP1
Pyridine SCHEMBL28259846 0.86 NOTUM (0.41) RAB9ANPC1SMN1; SMN2MEN1KMT2A
Acetic Acid SCHEMBL28149440 0.84 ADORA3 (0.41) RAB9ANPC1SMN1; SMN2MEN1KMT2A
Dimethyl Sulfone SCHEMBL17237872 0.84 PTGS2 (0.40) RAB9ANPC1SMN1; SMN2MEN1KMT2A
Carbamic Acid SCHEMBL474690 0.84 CASP1 (0.42) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL6135309 0.79 GPR55 (0.39) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL12327638 0.78 METAP2 (0.39)
SCHEMBL9315649 0.78 RAB9A (0.45) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL2679544 0.78 ENPP3 (0.47) RAB9ANPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3328744-B2 2002-09-30 JP claimed
EP-0686085-B1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES DOW CHEMICAL CO (US) 2001-04-04 EP claimed
US-5888434-A Process for making a microporous membrane from a blend containing a poly (phenylene sulfide) polymer, an amorphous polymer, and optionally a solvent THE DOW CHEMICAL COMPANY (US) 1999-03-30 US claimed
EP-0686085-A4 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES DOW CHEMICAL CO (US) 1996-03-13 EP claimed
EP-0686085-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1995-12-13 EP claimed
EP-0682591-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1995-11-22 EP claimed
WO-1994017985-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO claimed
WO-1994017974-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO claimed
US-8795781-B2 Methods and devices utilizing soluble conjugated polymers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-05 US disclosed
US-20080015269-A1 Hybrid polymer light-emitting devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-01-17 US disclosed
US-20060202616-A1 Multilayer polymer light-emitting diodes for solid state lighting applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-09-14 US disclosed
WO-2006094101-A1 MULTILAYER POLYMER LIGHT-EMITTING DIODES FOR SOLID STATE LIGHTING APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-09-08 WO disclosed
US-20060054886-A1 Methods and devices utilizing soluble conjugated polymers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-03-16 US disclosed
EP-0686085-B1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES DOW CHEMICAL CO (US) 2001-04-04 EP disclosed
US-5888434-A Process for making a microporous membrane from a blend containing a poly (phenylene sulfide) polymer, an amorphous polymer, and optionally a solvent THE DOW CHEMICAL COMPANY (US) 1999-03-30 US disclosed
EP-0686085-A4 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES DOW CHEMICAL CO (US) 1996-03-13 EP disclosed
EP-0686085-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1995-12-13 EP disclosed
EP-0682591-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1995-11-22 EP disclosed
WO-1994017985-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO disclosed
WO-1994017974-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO disclosed