Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014191 | 0.74 | MAPT (0.52) | CTSKC3AR1MAPTATMNPSR1 | |
| SCHEMBL9303530 | 0.73 | ATM (0.39) | CTSKC3AR1MAPTATMITGB3 | |
| SCHEMBL18764998 | 0.73 | HTT (0.50) | MAPTNPSR1 | |
| SCHEMBL5015698 | 0.72 | FPR2 (0.40) | CTSKMAPT | |
| SCHEMBL1706448 | 0.71 | CES1 (0.39) | — | |
| SCHEMBL3586130 | 0.70 | KDM4A (0.40) | NPSR1 | |
| SCHEMBL3400916 | 0.69 | CTSK (0.55) | CTSKCTSS | |
| SCHEMBL5014055 | 0.69 | CTSK (0.43) | CTSKMAPTATMNPSR1CTSS | |
| SCHEMBL5013649 | 0.68 | PCSK9 (0.47) | CTSKC3AR1ATMNPSR1CTSS | |
| SCHEMBL800492 | 0.67 | KMT2A (0.49) | C3AR1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |