Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014406 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7373327 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27410029 | 0.91 | KMT2A (0.47) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL21447860 | 0.91 | PPARG (0.50) | ALDH1A1KMT2AMMP12LMNA | |
| SCHEMBL21447925 | 0.87 | MGLL (0.46) | KMT2AMMP12LTA4H | |
| SCHEMBL22651565 | 0.87 | L3MBTL1 (0.53) | L3MBTL1MMP12LTA4HLAP3 | |
| SCHEMBL22502746 | 0.87 | MMP12 (0.50) | ALDH1A1KMT2AMMP12HCAR2 | |
| SCHEMBL19244967 | 0.87 | POLB (0.47) | ALDH1A1L3MBTL1KMT2AMMP12LMNA | |
| SCHEMBL28893772 | 0.86 | HCAR2 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1MMP12 | |
| SCHEMBL27743535 | 0.86 | HCAR2 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354408-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-11-12 | — | — | US | disclosed |
| US-7323489-B2 | Proline ester and preparation containing the same for percutaneous administration | TOAEIYO LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323489-B2 | Proline ester and preparation containing the same for percutaneous administration | TOAEIYO LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20050288232-A1 | Proline ester and preparation containing the same for percutaneous administration | TOAEIYO LTD (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-1538158-A1 | PROLINE ESTER AND PREPARATION CONTAINING THE SAME FOR PERCUTANEOUS ADMINISTRATION | Toaeiyo Ltd. (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-5703092-A | TREATING ARTHRITIS, OTHER INFLAMMATORY DISEASES MEDIATED BY MATRIX METALLOPROTEINASE AND/OR TUMOR NECROSIS FACTOR | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0495822-A1 | CARBOXYALKYL DIPEPTIDE INHIBITORS OF ENDOPEPTIDASES | SCHERING CORPORATION (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| WO-1991005796-A1 | CARBOXYALKYL DIPEPTIDE INHIBITORS OF ENDOPEPTIDASES | SCHERING CORPORATION (US) | 1991-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288232-A1 | Proline ester and preparation containing the same for percutaneous administration | AGTR1, NPPA, NPR1 | ALDH1A1 770/4885TDP1 2214/4885MAPK1 1174/4885 |
| US-20200354408-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | VIP, PREP, DNPEP | ALDH1A1 3037/4885TDP1 1835/4885MAPK1 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.