Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015111 | 0.88 | GNRHR (0.44) | GNRHRSCDDRD4DRD2DRD3 | |
| SCHEMBL2096350 | 0.84 | TTR (0.33) | GNRHRSCDDRD2KDM4EALDH1A1 | |
| SCHEMBL5016131 | 0.84 | ALDH1A1 (0.51) | GNRHRDRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL27666383 | 0.80 | GNRHR (0.43) | GNRHRSCDDRD4DRD2DRD3 | |
| SCHEMBL5013346 | 0.77 | KDM4E (0.45) | GNRHRDRD4DRD2DRD3KDM4E | |
| SCHEMBL2093128 | 0.76 | SCD (0.48) | SCD | |
| SCHEMBL5016197 | 0.75 | DRD2 (0.43) | GNRHRDRD4DRD2DRD3KDM4E | |
| SCHEMBL5015079 | 0.73 | DRD2 (0.41) | DRD4DRD2DRD3NPSR1RAB9A | |
| SCHEMBL5011693 | 0.72 | ADRA1A (0.45) | DRD2ALDH1A1HTR1AHTR2ATDP1 | |
| SCHEMBL2096352 | 0.72 | TTR (0.33) | GNRHRDRD2KDM4EALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |