Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016389 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1LMNAMAPK1 | |
| SCHEMBL1086088 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRL3MBTL1LMNAMAPK1 | |
| SCHEMBL5013588 | 0.75 | HSD11B1 (0.42) | ALDH1A1LMNAHTTSIGMAR1 | |
| SCHEMBL5012778 | 0.74 | TP53 (0.37) | ALDH1A1LMNARECQLHTTSIGMAR1 | |
| SCHEMBL5013535 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HTTKDM4ESIGMAR1 | |
| SCHEMBL5015096 | 0.70 | KMT2A (0.37) | ALDH1A1TSHRL3MBTL1LMNAP2RX7 | |
| SCHEMBL5011651 | 0.67 | CHRM2 (0.44) | ALDH1A1TSHRL3MBTL1LMNAMAPK1 | |
| SCHEMBL5011764 | 0.67 | HTT (0.44) | ALDH1A1TSHRL3MBTL1LMNAHTT | |
| SCHEMBL5011708 | 0.65 | CYP1A2 (0.45) | ALDH1A1TSHRL3MBTL1LMNAHTT | |
| SCHEMBL5066934 | 0.65 | KMT2A (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910381-A2 | SUBSTITUTED 1-OXA-3,8-DIAZASPIRO[4.5]-DECAN-2-ON- COMPOUNDS AND THE USE THEREOF FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007000325-A2 | SUBSTITUTED 1-OXA-3,8-DIAZASPIRO[4.5]-DECAN-2-ON- COMPOUNDS AND THE USE THEREOF FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2007-01-04 | — | — | WO | disclosed |