Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FPR3 | P25089 | 3/20 | 0.34 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023358 | 0.89 | NAMPT (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13201242 | 0.88 | FPR3 (0.40) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13201225 | 0.76 | FPR3 (0.42) | LMNAMEN1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL5022622 | 0.76 | MEN1 (0.38) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5023849 | 0.76 | LMNA (0.40) | LMNAMEN1TSHRFPR3FPR2 | |
| SCHEMBL13201237 | 0.74 | CCR5 (0.36) | — | |
| SCHEMBL14468476 | 0.71 | FPR3 (0.38) | L3MBTL1LMNAMEN1FPR3FPR2 | |
| SCHEMBL13201260 | 0.69 | LMNA (0.42) | L3MBTL1LMNAMEN1FPR3FPR2 | |
| SCHEMBL14048525 | 0.69 | LMNA (0.36) | L3MBTL1LMNAMEN1TSHRFPR3 | |
| SCHEMBL5025688 | 0.67 | LMNA (0.43) | L3MBTL1LMNASMN1; SMN2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632483-B1 | HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | AVENTIS PHARMA INC (US) | 2008-10-29 | — | — | EP | claimed |