Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FPR3 | P25089 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016836 | 0.89 | L3MBTL1 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13201225 | 0.87 | FPR3 (0.42) | NAMPTFPR3FPR2SMN1; SMN2MEN1 | |
| SCHEMBL5022622 | 0.81 | MEN1 (0.38) | NAMPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5023849 | 0.79 | LMNA (0.40) | NAMPTTSHRFPR3FPR2SMN1; SMN2 | |
| SCHEMBL13201242 | 0.76 | FPR3 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13201260 | 0.72 | LMNA (0.42) | FPR3FPR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3053060 | 0.72 | PDCD1 (0.35) | TSHRKMT2AALDH1A1MAPT | |
| SCHEMBL5025688 | 0.70 | LMNA (0.43) | NAMPTSMN1; SMN2ALDH1A1NPC1GAA | |
| SCHEMBL5023775 | 0.68 | DRD2 (0.37) | MEN1KMT2ANPC1 | |
| SCHEMBL13201108 | 0.68 | LMNA (0.38) | FPR3FPR2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632483-B1 | HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | AVENTIS PHARMA INC (US) | 2008-10-29 | — | — | EP | claimed |