SCHEMBL501701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL501907	0.93	HSD11B1 (0.40)	ALDH1A1NPC1HSD11B1MAPK1MAPT
	SCHEMBL16893272	0.83	HSD11B1 (0.47)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL1398386	0.80	ALDH1A1 (0.43)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL387181	0.79	HSD11B1 (0.50)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL3136709	0.79	HSD11B1 (0.50)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL961627	0.78	POLB (0.46)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL4261409	0.78	HSD11B1 (0.42)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL962244	0.77	HSD11B1 (0.40)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL14674097	0.76	ALDH1A1 (0.37)	ALDH1A1NPC1RECQLRAB9AHSD11B1
	SCHEMBL501700	0.76	ALDH1A1 (0.36)	ALDH1A1NPC1RECQLRAB9AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.