SCHEMBL501700

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL501906	0.93	KMT2A (0.36)	ALDH1A1NPC1MAPTHSD11B1TDP1
	SCHEMBL30029869	0.87	ALDH1A1 (0.34)	ALDH1A1RAB9ANPC1RECQLMAPT
	SCHEMBL1398384	0.81	ALDH1A1 (0.38)	ALDH1A1RECQLHSD11B1MEN1KMT2A
	SCHEMBL546400	0.79	KCNN4 (0.38)	ALDH1A1RAB9ANPC1RECQLMAPT
	Trifluoromethanesulfonic Acid SCHEMBL3136704	0.79	HSD11B1 (0.41)	ALDH1A1RAB9ANPC1RECQLMAPT
	Trifluoromethanesulfonic Acid SCHEMBL51512	0.79	HSD11B1 (0.41)	ALDH1A1RAB9ANPC1RECQLMAPT
	SCHEMBL546250	0.78	ALDH1A1 (0.33)	ALDH1A1RAB9ANPC1RECQLMAPT
	SCHEMBL29745785	0.77	HSD11B1 (0.40)	ALDH1A1RAB9ANPC1RECQLMAPT
	SCHEMBL2437122	0.77	HSD11B1 (0.40)	ALDH1A1RAB9ANPC1RECQLMAPT
	SCHEMBL246810	0.77	HTT (0.33)	ALDH1A1MAPTTDP1MEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.