SCHEMBL501907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL501701	0.93	ALDH1A1 (0.41)	HSD11B1KMT2ATSHRMEN1MAPK1
	SCHEMBL246811	0.82	KMT2A (0.36)	HSD11B1KMT2ATSHRHTTMEN1
	SCHEMBL4268824	0.80	HSD11B1 (0.37)	HSD11B1KMT2ATSHRHTTMEN1
	SCHEMBL13721631	0.78	HSD11B1 (0.35)	HSD11B1KMT2ATSHRHTTMEN1
	SCHEMBL15209913	0.78	ALDH1A1 (0.51)	KMT2ATSHRMEN1MAPK1MAPT
	SCHEMBL954202	0.77	HPGD (0.35)	HSD11B1KMT2AMEN1MAPK1SMN1; SMN2
	SCHEMBL3756015	0.77	MEN1 (0.44)	KMT2ATSHRMEN1MAPTHSD17B10
	SCHEMBL1484264	0.77	CA2 (0.40)	HSD11B1TSHRMAPTSMN1; SMN2HSD17B10
	SCHEMBL501412	0.76	HSD11B1 (0.38)	HSD11B1KMT2ATSHRMEN1MAPT
	SCHEMBL546553	0.75	KMT2A (0.33)	HSD11B1KMT2ATSHRHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.