Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.60 |
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | C1S | P09871 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12865158 | 0.94 | PARP1 (0.60) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL3087359 | 0.91 | TSHR (0.55) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL27704356 | 0.85 | TPMT (0.70) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL13917960 | 0.85 | HCAR1 (0.65) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL1363884 | 0.84 | PARP1 (0.50) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL11526256 | 0.84 | PARP1 (0.50) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL2468003 | 0.84 | PARP1 (0.50) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL22383502 | 0.84 | PARP1 (0.50) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL28069063 | 0.83 | CYP1A2 (0.50) | PARP1TPMTPRSS1PRSS2C1S | |
| SCHEMBL12021010 | 0.82 | TPMT (0.52) | PARP1TPMTPRSS1PRSS2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180188-B2 | Antifibrotic compounds and related methods | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-12-31 | — | — | US | claimed |
| CN-118063395-A | Preparation method of anti-AIDS drug Ai Nuowei Lin Zhongjian | 成都艾迪医药技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117126487-A | Near infrared transmission resin composition and preparation method and application thereof | 四川大学 | 2023-11-28 | — | — | CN | claimed |
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| EP-4153177-A1 | ANTIFIBROTIC COMPOUNDS AND RELATED METHODS | Florida State University Research Foundation, Inc. (US) | 2023-03-29 | — | — | EP | claimed |
| US-20230090542-A1 | Antifibrotic Compounds And Related Methods | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2023-03-23 | — | — | US | claimed |
| US-11548874-B2 | Antifibrotic compounds and related methods | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-01-10 | — | — | US | claimed |
| CN-114835926-A | Preparation method of antibacterial bright red chinlon 6 master batch and antibacterial cool feeling bright red chinlon 6 filament | 福建景丰科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| US-20210363131-A1 | Antifibrotic Compounds And Related Methods | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2021-11-25 | — | — | US | claimed |
| WO-2021236410-A1 | ANTIFIBROTIC COMPOUNDS AND RELATED METHODS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-11-25 | — | — | WO | claimed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-07-15 | — | — | US | claimed |
| WO-2004056820-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY LLC (US) | 2004-07-08 | — | — | WO | claimed |
| US-20030232823-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-12-18 | — | — | US | claimed |
| WO-2003059899-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL FORMULATIONS CONTAINING THEM AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| US-4084056-A | FROM AN AROMATIC AMIDE AND A GROUP IA OR IIA HYPOCHLORITE WITH A CARBAMATE SUBSTITUTED PHENOL | AB BOFORS (SW) | 1978-04-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232823-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof | NR3C1, NR3C2, MC2R | PARP1 3616/4885TPMT 629/4885PRSS1 479/4885 |
| US-11548874-B2 | Antifibrotic compounds and related methods | COL1A1, COL2A1, COLGALT1 | PARP1 2402/4885TPMT 1976/4885PRSS1 829/4885 |
| US-12180188-B2 | Antifibrotic compounds and related methods | COL1A1, COL2A1, COLGALT1 | PARP1 2402/4885TPMT 1976/4885PRSS1 829/4885 |
| US-20230090542-A1 | Antifibrotic Compounds And Related Methods | COL1A1, COL2A1, COLGALT1 | PARP1 2402/4885TPMT 1976/4885PRSS1 829/4885 |
| US-20210363131-A1 | Antifibrotic Compounds And Related Methods | COL1A1, COL2A1, COLGALT1 | PARP1 2402/4885TPMT 1976/4885PRSS1 829/4885 |
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | XDH, TBXA2R, TBXAS1 | PARP1 1401/4885TPMT 904/4885PRSS1 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.