SCHEMBL501906

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL501700	0.93	ALDH1A1 (0.36)	KMT2AHTTMEN1TSHRNPC1
	SCHEMBL246810	0.83	HTT (0.33)	KMT2AHTTMEN1TSHRELANE
	SCHEMBL501595	0.81	PRKCA (0.33)	ELANEPRKCA
	SCHEMBL1001524	0.81	KDM4E (0.41)	KMT2AHTTMEN1TSHRNPC1
	SCHEMBL4268815	0.80	KMT2A (0.34)	KMT2AHTTMEN1TSHRNPC1
	SCHEMBL543694	0.80	MEN1 (0.38)	KMT2AHTTMEN1TSHRALDH1A1
	SCHEMBL30029869	0.79	ALDH1A1 (0.34)	KMT2AMEN1NPC1HSD11B1MAPT
	SCHEMBL6117166	0.78	HSD11B1 (0.32)	KMT2AHTTMEN1TSHRELANE
	SCHEMBL2221325	0.78	HTT (0.31)	KMT2AHTTMEN1TSHRELANE
	SCHEMBL10003832	0.78	TDP1 (0.34)	HTTELANEHSD11B1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.