SCHEMBL502076

SCHEMBL502076

O=C1C=C(N(CCCF)Cc2ccc(Cl)nc2)CO1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31
PSENEN Q9NZ42 1/20 0.31
CHRNA1 P02708 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KDM1A O60341 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29845433 1.00 PSEN1 (0.31) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL120449 0.93 CHRNA1 (0.32) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1800501 0.91 CHRNA1 (0.32) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1796525 0.89 PSEN1 (0.31) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1801176 0.86 ALDH1A1 (0.34) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL28892254 0.84 MDM2 (0.34) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL2893249 0.83 ALDH1A1 (0.35) ALDH1A1
SCHEMBL29394548 0.83 KDM1A (0.32) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL123283 0.83 KDM1A (0.32) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL3025243 0.82 L3MBTL1 (0.42) ALDH1A1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP claimed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US claimed
WO-2021069628-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO claimed
EP-3772943-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE Bayer Aktiengesellschaft (DE) 2021-02-17 EP claimed
WO-2019197635-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO claimed
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP disclosed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
WO-2021069628-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO disclosed
EP-3772943-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE Bayer Aktiengesellschaft (DE) 2021-02-17 EP disclosed
WO-2019197635-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO disclosed
EP-2004635-B1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER IP GMBH (DE) 2015-09-23 EP disclosed
EP-2004635-B1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER IP GMBH (DE) 2015-09-23 EP disclosed
US-8106211-B2 Substituted enaminocarbonyl compounds BAYER CROPSCIENCE AG (DE) 2012-01-31 US disclosed
US-8106211-B2 Substituted enaminocarbonyl compounds BAYER CROPSCIENCE AG (DE) 2012-01-31 US disclosed
EP-2327304-A1 Use of substituted enaminocarbonyl compounds for combating animal pests Bayer CropScience AG (DE) 2011-06-01 EP disclosed
EP-2327304-A1 Use of substituted enaminocarbonyl compounds for combating animal pests Bayer CropScience AG (DE) 2011-06-01 EP disclosed
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG 2009-10-08 US disclosed
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG 2009-10-08 US disclosed
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG 2009-10-08 US disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS SGMS2, SGMS1, CYP51A1 PSEN1 1250/4885PSEN2 1366/4885APH1B 1030/4885
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS DDT, NPEPPS, L3MBTL4 PSEN1 2614/4885PSEN2 2429/4885APH1B 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.