Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193213 | 1.00 | MEN1 (0.56) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL14978829 | 0.91 | L3MBTL1 (0.49) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL18231290 | 0.87 | HTT (0.56) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL24452828 | 0.87 | MEN1 (0.47) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL20817495 | 0.86 | NPSR1 (0.47) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL30660755 | 0.86 | NPSR1 (0.47) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL24453262 | 0.86 | MEN1 (0.46) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL24453264 | 0.85 | NPSR1 (0.46) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL14010911 | 0.84 | LMNA (0.58) | MEN1KMT2AALOX12NPSR1HPGD | |
| SCHEMBL24453266 | 0.83 | NPSR1 (0.44) | MEN1KMT2AALOX12NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203497-A1 | DYNAMIN 2 INHIBITOR FOR THE TREATMENT OF CENTRONUCLEAR MYOPATHIES | UNIVERSITE DE STRASBOURG (FR) | 2023-06-29 | — | — | US | claimed |
| US-20210196732-A1 | Drug Targets of Delayed Aging and Human Brain Diseases | TEXAS TECH UNIVERSITY SYSTEM | 2021-07-01 | — | — | US | claimed |
| EP-3286317-B1 | DYNAMIN 2 INHIBITOR FOR THE TREATMENT OF DUCHENNE'S MUSCULAR DYSTROPHY | UNIV STRASBOURG (FR) | 2021-02-24 | — | — | EP | claimed |
| US-20190307749-A1 | Mitochondria-Division Inhibitor 1 Protects Against Amyloid-B Induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease | TEXAS TECH UNIVERSITY SYSTEM | 2019-10-10 | — | — | US | claimed |
| WO-2018098484-A1 | DRUG TARGETS OF DELAYED AGING AND HUMAN BRAIN DISEASES | TEXAS TECH UNIVERSITY SYSTEM (US) | 2018-05-31 | — | — | WO | claimed |
| US-20160264976-A1 | DYNAMIN 2 INHIBITOR FOR THE TREATMENT OF CENTRONUCLEAR MYOPATHIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-09-15 | — | — | US | claimed |
| WO-2005051974-A2 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-06-09 | — | — | WO | claimed |
| US-20050038051-A1 | Novel molecules for regulating cell death | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | claimed |
| EP-4702130-A1 | HYPOXIA-RESISTANT IMMUNE CELLS FOR SUSTAINED PERSISTENCE AND FUNCTIONALITY IN THE HYPOXIC TUMOR MICROENVIRONMENT | Universiteit Antwerpen (BE) | 2026-03-04 | — | — | EP | disclosed |
| US-12208108-B2 | Drug targets of delayed aging and human brain diseases | TEXAS TECH UNIVERSITY SYSTEM (US) | 2025-01-28 | — | — | US | disclosed |
| WO-2024223860-A1 | HYPOXIA-RESISTANT IMMUNE CELLS FOR SUSTAINED PERSISTENCE AND FUNCTIONALITY IN THE HYPOXIC TUMOR MICROENVIRONMENT | UNIVERSITEIT ANTWERPEN (BE) | 2024-10-31 | — | — | WO | disclosed |
| EP-4397770-A1 | STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS | PreAnalytiX GmbH (CH) | 2024-07-10 | — | — | EP | disclosed |
| EP-4311546-A1 | COMBINATION THERAPY FOR MYOPATHIES | Dynacure (FR) | 2024-01-31 | — | — | EP | disclosed |
| EP-3401406-B1 | STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS | PREANALYTIX GMBH (CH) | 2023-11-29 | — | — | EP | disclosed |
| US-20130045443-A1 | POLYMER, RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2013-02-21 | — | — | US | disclosed |
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-20 | — | — | US | disclosed |
| WO-2005051974-A2 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050038051-A1 | Novel molecules for regulating cell death | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | AIFM1, BAX, HSPE1 | MEN1 4201/4885KMT2A 4447/4885ALOX12 3239/4885 |
| US-20190307749-A1 | Mitochondria-Division Inhibitor 1 Protects Against Amyloid-B Induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease | NLN, AIFM1, NDUFAB1 | MEN1 3382/4885KMT2A 4480/4885ALOX12 3463/4885 |
| US-12208108-B2 | Drug targets of delayed aging and human brain diseases | DNM1L, DNM1, DNM2 | MEN1 3108/4885KMT2A 2173/4885ALOX12 4248/4885 |
| US-20210196732-A1 | Drug Targets of Delayed Aging and Human Brain Diseases | DNM1L, DNM1, DNM2 | MEN1 3108/4885KMT2A 2173/4885ALOX12 4248/4885 |
| US-20050038051-A1 | Novel molecules for regulating cell death | AIFM1, BAX, HSPE1 | MEN1 4201/4885KMT2A 4447/4885ALOX12 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.