Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL5027651 | 0.93 | MEN1 (0.33) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL4924822 | 0.69 | — | — | |
| SCHEMBL777727 | 0.67 | TSHR (0.33) | TSHR | |
| Tetrafluoroethylene SCHEMBL28834560 | 0.67 | TSHR (0.40) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL301953 | 0.65 | — | — | |
| Lithium Ion SCHEMBL8907904 | 0.65 | — | — | |
| SCHEMBL50057 | 0.65 | — | — | |
| SCHEMBL778375 | 0.62 | — | — | |
| SCHEMBL5026148 | 0.62 | TSHR (0.38) | TSHR | |
| SCHEMBL2597130 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574124-A | Low-water-absorption polymer cement waterproof coating and preparation method thereof | 成都市水泷头化工科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-109734564-B | Method for synthesizing trifluoroethyl aromatic compound | 南京理工大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-111574124-A | Low-water-absorption polymer cement waterproof coating and preparation method thereof | 成都市水泷头化工科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111574124-A | Low-water-absorption polymer cement waterproof coating and preparation method thereof | 成都市水泷头化工科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| US-7414102-B2 | Polymer electrolyte of high durability and a production process thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-08-19 | — | — | US | disclosed |
| US-20050004335-A1 | Polymer electrolyte of high durability and a production process thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2005-01-06 | — | — | US | disclosed |