Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.76 |
| ▸ | CTSS | P25774 | 4/20 | 0.76 |
| ▸ | CTSK | P43235 | 4/20 | 0.76 |
| ▸ | CTSB | P07858 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | CTSH | P09668 | 1/20 | 0.53 |
| ▸ | CASP14 | P31944 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346331 | 0.85 | CTSL (0.98) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL5031319 | 0.83 | NFKB1 (0.56) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL5031260 | 0.80 | RAB9A (0.62) | CTSLCTSSCTSKCTSBRAB9A | |
| SCHEMBL13326008 | 0.79 | RAB9A (0.75) | CTSLCTSSCTSKMEN1KMT2A | |
| SCHEMBL14600703 | 0.79 | RAB9A (0.75) | CTSLCTSSCTSKMEN1KMT2A | |
| SCHEMBL20938665 | 0.79 | RAB9A (0.75) | CTSLCTSSCTSKMEN1KMT2A | |
| SCHEMBL3475933 | 0.79 | NPC1 (0.67) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL5031277 | 0.79 | CTSL (0.61) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL27223333 | 0.79 | ABCG2 (0.68) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL13326014 | 0.77 | GALR2 (0.67) | CTSLCTSSCTSKCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335770-B2 | Triazine compounds and their analogs, compositions, and methods | REDDY U5 THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7335770-B2 | Triazine compounds and their analogs, compositions, and methods | REDDY U5 THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7335770-B2 | Triazine compounds and their analogs, compositions, and methods | REDDY U5 THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-20050227983-A1 | Triazine compounds and their analogs, compositions, and methods | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227983-A1 | Triazine compounds and their analogs, compositions, and methods | MYLK, SMAD3, GID4 | CTSL 3954/4885CTSS 3208/4885CTSK 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.