Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686652 | 0.97 | TSHR (0.41) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 | |
| Lithium Ion SCHEMBL9625582 | 0.97 | TSHR (0.41) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 | |
| Acrylamide SCHEMBL3827026 | 0.91 | TSHR (0.37) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 | |
| Potassium Ion SCHEMBL3660409 | 0.86 | TSHR (0.44) | TSHRZDHHC20ZDHHC2TGM2ALDH1A1 | |
| SCHEMBL28598555 | 0.84 | ZDHHC20 (0.45) | TSHRZDHHC20ZDHHC2TGM2MAPK1 | |
| SCHEMBL29257467 | 0.84 | ZDHHC20 (0.45) | TSHRZDHHC20ZDHHC2TGM2MAPK1 | |
| SCHEMBL1561975 | 0.83 | TSHR (0.44) | TSHRZDHHC20ZDHHC2TGM2ALDH1A1 | |
| Lithium Ion SCHEMBL6898224 | 0.83 | TSHR (0.44) | TSHRZDHHC20ZDHHC2TGM2ALDH1A1 | |
| SCHEMBL21951 | 0.83 | TSHR (0.44) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 | |
| Ammonia Solution, Strong SCHEMBL139207 | 0.81 | TSHR (0.42) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311415-A1 | Use of a Latex Composition Having at Least One Ureido Function For Adhering to Wood | LAPEYRE (FR) | 2008-12-18 | — | — | US | disclosed |
| EP-0374709-B1 | PROCESS FOR CONTINUOUSLY PREPARING LIQUID-ABSORBING CURED POLYMERS | Chemie Linz Gesellschaft m.b.H. (AT) | 1993-09-29 | — | — | EP | disclosed |
| EP-0374709-A2 | Process for continuously preparing liquid-absorbing cured polymers | Chemie Linz Gesellschaft m.b.H. (AT) | 1990-06-27 | — | — | EP | disclosed |