Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL9625585 | 0.97 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL2809548 | 0.97 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acrylamide SCHEMBL7738764 | 0.91 | TSHR (0.35) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29737440 | 0.87 | BBOX1 (0.34) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28300 | 0.83 | ZDHHC20 (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL686653 | 0.81 | ZDHHC20 (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL28069295 | 0.81 | ZDHHC20 (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Ammonia Solution, Strong SCHEMBL139208 | 0.81 | ZDHHC20 (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acrylic Acid SCHEMBL7528349 | 0.79 | ZDHHC20 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acrylamide SCHEMBL8157330 | 0.78 | ZDHHC20 (0.40) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926577-B1 | USE OF A LATEX COMPOSITION HAVING AT LEAST ONE UREIDO FUNCTION FOR ADHERING TO WOOD | LAPEYRE (FR) | 2013-01-02 | — | — | EP | claimed |
| US-20080311415-A1 | Use of a Latex Composition Having at Least One Ureido Function For Adhering to Wood | LAPEYRE (FR) | 2008-12-18 | — | — | US | claimed |
| US-20080311415-A1 | Use of a Latex Composition Having at Least One Ureido Function For Adhering to Wood | LAPEYRE (FR) | 2008-12-18 | — | — | US | disclosed |