Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | EBP | Q15125 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12610941 | 0.82 | CYP2D6 (0.74) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| SCHEMBL1405290 | 0.82 | CYP2D6 (0.74) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| Hydrochloric Acid SCHEMBL10505479 | 0.80 | CYP2D6 (0.72) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| Bromide SCHEMBL1173547 | 0.80 | CYP2D6 (0.72) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| Benzofuran SCHEMBL29288365 | 0.74 | AGXT (0.46) | LTA4HKCNH2KCNA3TSHR | |
| SCHEMBL22224170 | 0.74 | ALDH1A1 (0.63) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| SCHEMBL6676718 | 0.73 | LTA4H (0.62) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| SCHEMBL9706125 | 0.73 | EBP (0.72) | CYP2D6HTTCYP1A2LTA4HCYP2C9 | |
| Benzofuran SCHEMBL5035533 | 0.72 | KCNA3 (0.33) | KCNH2ADRA2ACHRM5ADRA2BHTR2A | |
| Benzofuran SCHEMBL28188884 | 0.72 | CA4 (0.54) | CYP2D6CYP1A2LTA4HCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664267-B2 | Parenteral solution containing amiodarone in NNDMA (N,N,-Dimethylacetamide) | ACADEMIC PHARMACEUTICALS INCORPORATED (US) | 2014-03-04 | — | — | US | disclosed |
| US-20080255229-A1 | Parenteral solution containing amiodarone in NNDMA (N,N,-Dimethylacetamide) | ACADEMIC PHARMACEUTICALS INCORPORATED | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255229-A1 | Parenteral solution containing amiodarone in NNDMA (N,N,-Dimethylacetamide) | TNNC1, NPPA, TNNI3 | CYP2D6 106/4885HTT 3989/4885CYP1A2 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.