Isopulegol

Isopulegol

SCHEMBL5043480

C=C(C)[C@H]1CC[C@@H](C)C[C@@H]1O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 2/20 0.45
▸ TRPM8 Q7Z2W7 2/20 0.45
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA4 P22748 1/20 0.33
▸ EPHX1 P07099 1/20 0.31
▸ CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopulegol SCHEMBL8814498 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8816208 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8818931 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL18828953 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL15013625 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8813812 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL20903638 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL20903648 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL20681722 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8618394 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739648-A1 PHOTOISOMERIZATION OF GERANIAL AND NERAL BASF SE (DE) 2026-05-13 — — EP disclosed
US-20260060244-A1 WATER-BASED PEST CONTROL COMPOSITIONS JOHNSON & SON INC S C (US) 2026-03-05 — — US disclosed
US-20250386821-A1 POWDER-BASED PEST CONTROL COMPOSITIONS JOHNSON & SON INC S C (US) 2025-12-25 — — US disclosed
US-12446586-B2 Oil-based insecticidal and insect repellent compositions S. C. JOHNSON & SON, INC. (US) 2025-10-21 — — US disclosed
US-20250295122-A1 OIL-BASED INSECTICIDAL AND INSECT REPELLENT COMPOSITIONS JOHNSON & SON INC S C (US) 2025-09-25 — — US disclosed
WO-2025011972-A1 PHOTOISOMERIZATION OF GERANIAL AND NERAL BASF SE (DE) 2025-01-16 — — WO disclosed
EP-4432837-A1 OIL-BASED INSECTICIDAL AND INSECT REPELLENT COMPOSITIONS S.C. Johnson & Son, Inc. (US) 2024-09-25 — — EP disclosed
EP-4432838-A1 WATER-BASED INSECTICIDAL AND INSECT REPELLENT COMPOSITIONS S. C. Johnson & Son, Inc. (US) 2024-09-25 — — EP disclosed
EP-4432840-A1 WATER-BASED INSECTICIDAL AND INSECT REPELLENT COMPOSITIONS S. C. Johnson & Son, Inc. (US) 2024-09-25 — — EP disclosed
EP-4432839-A1 OIL-BASED INSECTICIDAL AND INSECT REPELLENT COMPOSITIONS S.C. Johnson & Son, Inc. (US) 2024-09-25 — — EP disclosed
US-20100191021-A1 PROCESS FOR PREPARATION OF MENTHOL BY HYDROGENATION OF ISOPULEGOL BASF SE (DE) 2010-07-29 — — US disclosed
US-7608742-B2 Diarylphenoxy aluminum compounds BASF AKTIENGESELLSCHAFT (DE) 2009-10-27 — — US disclosed
US-7608742-B2 Diarylphenoxy aluminum compounds BASF AKTIENGESELLSCHAFT (DE) 2009-10-27 — — US disclosed
WO-2009068444-A2 METHOD FOR PRODUCING OPTICALLY ACTIVE, RACEMIC MENTHOL BASF SE (DE) 2009-06-04 — — WO disclosed
WO-2009013192-A1 PROCESS FOR PREPARATION OF MENTHOL BY HYDROGENATION OF ISOPULEGOL BASF SE (DE) 2009-01-29 — — WO disclosed
US-20080269481-A1 Compounds and methods for the treatment or prevention of Flavivirus infections VIROCHEM PHARMA INC. (CA) 2008-10-30 — — US disclosed
EP-1858903-B1 DIARYLPHENOXY ALUMINUM COMPOUNDS BASF SE (DE) 2008-10-08 — — EP disclosed
US-20080167504-A1 reacting a bis(diarylphenol) ligand with an alkylaluminum compound and/or a complex aluminum hydride; producing isopulegol by cyclization of citronellal in the presence of diarylphenoxyaluminum compounds as catalysts BASF AKTIENGESELLSCHAFT (DE) 2008-07-10 — — US disclosed
US-20080167504-A1 reacting a bis(diarylphenol) ligand with an alkylaluminum compound and/or a complex aluminum hydride; producing isopulegol by cyclization of citronellal in the presence of diarylphenoxyaluminum compounds as catalysts BASF AKTIENGESELLSCHAFT (DE) 2008-07-10 — — US disclosed
EP-1942111-A1 Diarylphenoxy aluminum compounds BASF SE (DE) 2008-07-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167504-A1 reacting a bis(diarylphenol) ligand with an alkylaluminum compound and/or a complex aluminum hydride; producing isopulegol by cyclization of citronellal in the presence of diarylphenoxyaluminum compounds as catalysts ACSL3, ACSL1, ACSL5 TRPA1 42/4885TRPM8 69/4885CA1 120/4885
US-20250386821-A1 POWDER-BASED PEST CONTROL COMPOSITIONS CLK3, MERTK, SYMPK TRPA1 555/4885TRPM8 685/4885CA1 3693/4885
US-20080269481-A1 Compounds and methods for the treatment or prevention of Flavivirus infections ZC3HAV1, ZYX, ZFX TRPA1 1477/4885TRPM8 2450/4885CA1 4205/4885
US-20100191021-A1 PROCESS FOR PREPARATION OF MENTHOL BY HYDROGENATION OF ISOPULEGOL NISCH, HNMT, UCHL5 TRPA1 575/4885TRPM8 911/4885CA1 1401/4885
US-20260060244-A1 WATER-BASED PEST CONTROL COMPOSITIONS SGMS2, TGFBR2, SGMS1 TRPA1 7/4885TRPM8 18/4885CA1 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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